Background: Breast cancer is one of the most common worldwide malignancies among women. Biological data suggest that damage induced by endogenous and exogenous factors affects the integrity of DNA and associated with susceptibility to breast cancer. Single nucleotide polymorphisms (SNPs) in DNA repair genes can associated with differences in the repair efficiency of DNA damage and may affect br...

background: organophosphorus pesticides has been widely used in agriculture fields to control various crop insects and their extensive use pose human life at threat because of their adverse effects on human health. in this study, we checked the effects of gst polymorphism on ameliorative effect of curcumin and carvacrol against dna damages. methods: comet assay was used to assess the dna damage...

an attempt has been made to analyze the distribution of the beta-lactoglobulin genotype in swamp buffaloes and murrah buffaloes utilizing polymerase chain reaction-restriction fragment length polymorphism(pcr-rflp). blood samples were taken from 50 swamp buffaloes and 50 murrah buffaloes. the dna was extracted by the phenol-chloroform method. the pcr-rflp was performed using beta-lactoglobulin ...

The DMA (DM ? chain) gene, a member of non-classical MHC class II plays an important role in the process presenting antigen peptides by producing DM protein. This study aimed to identify polymorphism gene and their associations with disease resistance traits such as total IgY concentration ND antibody titers IPB-D2 chicken line. sample used was 101 chickens consisted 81 G0 (53 female 28 male) 2...

BACKGROUND: Interaction between estrogen and receptor (ER) takes part in the regulation differentiation of breast tumorigenesis. Some ERα polymorphisms, including rs3798577, are reported to be associated with risk aggressiveness carcinoma since site was targeted by microRNA, which can further modulate expression. Hence, this study conducted disclose possible role SNP rs3798577 on patients.METHO...

Molecular markers and mapping are used to analyze an organism’s genes. They allow the selection of target genetic areas based on marker genotype (and not trait phenotype), facilitate study variability diversity, create linkage maps, follow individuals or lines carrying certain may be select parental genotypes, remove drag in back-crossing, choose difficult-to-measure characteristics. Due a lack...