Background & aim: The developing countries have the contraceptive prevalence rate of 43%. Contraceptive discontinuation accounts for a large number of unintended pregnancies in these countries. The present study aimed to investigate the factors associated with Cyclofem discontinuation. Methods: This historical cohort study was conducted on 198 females, selected through cluster and Poisson sampl...

A case of acute extrapyramidal manifestations consisting of dystonia and akathisia following abrupt discontinuation of propranolol is reported. She responded well to oral propranolol and intramuscular diazepam. Extrapyramidal symptoms have commonly been associated with acute or chronic administration of neuroleptic drugs. There have been reports of a substantial number of cases with simila...

background : exclusive nutrition with breastfeeding is the health provider of the infant and mothers and its continuing would provide more advantages. exclusive nutrition on different communities is affected by different factors. this study aimed to determine continuous exclusive breastfeeding and some of the related factors. methods : this was a descriptive-analysis prospective study. the stud...

Hyperthyroidism is a common disease and one of the best methods for its treatment is radioiodine therapy. Treatment with antithyroid drugs brings patients to euthyroidism before radioiodine therapy. Antithyroid drugs should be discontinued before radioiodine therapy to increase thyroid uptake. The purpose of this study was to determine the optimal time of methimazole (MTZ) discontinuation...

Objective: Although dapoxetine is the only oral pharmacological agent approved for the treatment of premature ejaculation (PE) and is very effective, its discontinuation rate is high compared to PDE5 inhibitors in patients with erectile dysfunction (ED). This study assessed the discontinuation rate of dapoxetine treatment in patients with PE and the reasons for discontinuation a clinical settin...

OBJECTIVES To study the long term tolerance of parenteral gold and subsequent drug treatment in patients with rheumatoid arthritis, including prediction of outcome and 'survival' of sequential treatments. METHODS A retrospective cohort study of 376 patients was made, including a detailed screening of 237 patients treated in 1989. Reasons for discontinuing treatment were analysed in life table...

BACKGROUND Despite the widespread use of highly effective contraceptive methods in France, one in every three pregnancies is unintended. Among women experiencing an unintended pregnancy leading to an abortion, half had changed their contraceptive method in the 6 months preceding the abortion, in most cases switching to a less-effective method or to no method at all. This study provides estimate...