نتایج جستجو برای: directly observed treatment dot

تعداد نتایج: 2390376  

Journal: :Clinical infectious diseases : an official publication of the Infectious Diseases Society of America 2002
Jennifer Adelson Mitty Valerie E Stone Michael Sands Grace Macalino Timothy Flanigan

The principle of directly observed therapy (DOT) has its roots in the treatment of tuberculosis (TB), for which DOT programs have improved cure rates in hard-to-reach populations. Human immunodeficiency virus (HIV) and TB affect similar populations, and there are concerns about both regarding the development of drug resistance associated with poor adherence to therapy. Accordingly, DOT may bene...

Journal: :Curationis 2002
K Peltzer H Onya P Seoka F M Tladi R N Malema

The aim of this study is to compare and contrast health beliefs, demographic and socio-economic variables, causative beliefs, knowledge, health-seeking behaviour and health provider-patient interaction of compliant and non-compliant tuberculosis patients. The sample included 219 consecutive new sputum-smear and/or culture positive pulmonary tuberculosis patients registered between October 1999 ...

Journal: :AIDS patient care and STDs 2008
Mindy Ma Billy R Brown Melissa Coleman Jeffrey L Kibler Helen Loewenthal Jennifer A Mitty

Recently, modified directly observed therapy (MDOT) has emerged as a promising intervention to address nonadherence for hard-to-reach populations infected with HIV. To date, there are no existing data on MDOT focusing exclusively on African Americans. The present study sought to determine the feasibility of MDOT among 31 HIV-seropositive African American substance users in the South. An outreac...

Journal: :Tropical medicine & international health : TM & IH 2007
Thomas S Moulding

New international standards no longer require directly observed therapy for all tuberculosis (TB) patients, but state that practitioners must be capable of assessing adherence and addressing poor adherence. Mass-produced electronic medication monitors, which record removal of medication from a container, could help overcome the problem of assessing treatment adherence accurately even in poor co...

Journal: :Journal of Clinical Tuberculosis and Other Mycobacterial Diseases 2021

Journal: :The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease 2016
M R O'Donnell A Daftary M Frick Y Hirsch-Moverman K R Amico M Senthilingam A Wolf J Z Metcalfe P Isaakidis J L Davis J R Zelnick J C M Brust N Naidu M Garretson D R Bangsberg N Padayatchi G Friedland

BACKGROUND Despite renewed focus on molecular tuberculosis (TB) diagnostics and new antimycobacterial agents, treatment outcomes for patients co-infected with drug-resistant TB and human immunodeficiency virus (HIV) remain dismal, in part due to lack of focus on medication adherence as part of a patient-centered continuum of care. OBJECTIVE To review current barriers to drug-resistant TB-HIV ...

Journal: :Thorax 2014
Charlotte Anderson Jacqueline White Ibrahim Abubakar Marc Lipman Surinder Tamne Sarah R Anderson Jennifer Dekoningh Susan Dart

Cohort review has been used internationally to support tuberculosis (TB) control. We describe its first use in the UK by a London TB service. Improvements were noted in case management and contact tracing, weaknesses identified and important service changes put in place. Key areas of impact were directly observed therapy (DOT) provision (a greater proportion of cases offered DOT, and in respons...

Journal: :South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde 1997
D Wilkinson K Floyd C F Gilks

OBJECTIVE To conduct an economic analysis of the Hlabisa community-based directly observed therapy management strategy for tuberculosis and to project costs of three alternative strategies. SETTING Hlabisa health district, KwaZulu-Natal, South Africa. METHODS An economic analysis comparing the current tuberculosis management strategy in Hlabisa with three alternative strategies (the Hlabisa...

2017
Elizabeth Lawlor Holzschuh Stacie Province Krystle Johnson Caitlin Walls Cathy Shemwell Gary Martin Amy Showalter Jennifer Dunlay Andrew Conyers Phil Griffin Nancy Tausz

Tuberculosis (TB) is caused by the bacterium Mycobacterium tuberculosis and is spread from person to person through the air. TB can be spread in congregate settings, such as school environments, to varying degrees, based on factors including duration of contact and air ventilation (1); therefore, evaluating potential contacts and exposures can be challenging. In February 2015, a student at a Ka...

Journal: :The Southeast Asian journal of tropical medicine and public health 2011
Wanchai Maneeboonyang Saranath Lawpoolsri Supalarp Puangsa-Art Surapon Yimsamran Nipon Thanyavanich Pitak Wuthisen Sutthiporn Prommongkol Wuthichai Chaimongkul Prasert Rukmanee Natefa Rukmanee Irwin F Chavez Kasinee Buchachart Srivicha Krudsood Pratap Singhasivanon

This study was carried out from April 2005 to June 2006 to evaluate the recurrence of P. vivax malaria infection in relation to drug compliance along the Thai-Myanmar border in Ratchaburi, Thailand. Ninety-two patients with vivax malaria were sequentially assigned to 2 groups. Both groups received a standard dose of chloroquine (total dose = 2.5 g) for 3 days and primaquine (total dose = 210 mg...

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