The severity of urinary tract infection (UTI) reflects the quality and magnitude of the host response. While strong local and systemic innate immune activation occurs in patients with acute pyelonephritis, the response to asymptomatic bacteriuria (ABU) is low. The immune response repertoire in ABU has not been characterized, due to the inherent problem to distinguish bacterial differences from ...

Escherichia coli is the most common organism associated with asymptomatic bacteriuria (ABU) in humans. In contrast to uropathogenic E. coli (UPEC) that cause symptomatic urinary tract infection, very little is known about the mechanisms by which these strains colonize the urinary tract. Here, we have investigated the biofilm-forming capacity on abiotic surfaces of groups of ABU strains and UPEC...

Given H a real Hilbert space and Φ : H → R a smooth C function, we study the dynamical system (DIN) ẍ(t) + αẋ(t) + β∇Φ(x(t))ẋ(t) +∇Φ(x(t)) = 0 where α and β are positive parameters. The inertial term ẍ(t) acts as a singular perturbation and, in fact, regularization of the possibly degenerate classical Newton continuous dynamical system ∇Φ(x(t))ẋ(t)+∇Φ(x(t)) = 0. We show that (DIN) is a well-pos...

In aquatic ecosystems, carbon (C) availability strongly influences nitrogen (N) dynamics. One manifestation of this linkage is the importance in the dissolved organic matter (DOM) pool of dissolved organic nitrogen (DON), which can serve as both a C and an N source, yet our knowledge of how specific properties of DOM influence N dynamics are limited. To empirically examine the impact of labile ...

BACKGROUND Postsurgical treatment of ductal intraepithelial neoplasia (DIN) with standard doses of tamoxifen has not reached a consensus yet. Given positive results of low-dose tamoxifen on breast cancer biomarkers modulation, we analyzed a large cohort of DIN patients treated with low-dose tamoxifen or no treatment as per institutional guidelines. PATIENTS AND METHODS All consecutive women o...

Monthly time series of nutrient pools and transport in the Baltic Entrance were computed for the period 1974–1999 from a combination of hydrodynamic model results and observational data obtained in national monitoring programmes. Significant seasonal variations in both nutrient pools and transport were found. For example, inflowing dense nutrient-rich Skagerrak water causes net transport of dis...

Spaţiile virtuale 3D devin din ce în ce mai mult utilizate, de la jocuri până la aplicaţii industriale, medicale, militare sau ştiinţifice. Unele dintre cele mai importante aplicaţii ale acestora sunt în e-learning şi edutainment. Lucrarea de faţă prezintă elementele constitutive şi aspecte ale creării unui”muzeu virtual 3D”, pornind de la experienţa autorilor în dezvoltarea aplicaţiei software...

The concentration of dissolved inorganic nitrogen (DIN) in the porewaters of shallow-water tropical marine sediments can be as high as 50-100 µM, at sediment depths of shallow as 20 cm. These concentrations are at least two-orders of magnitude greater than the DIN concentration in the overlying water. High porewater concentrations, and the resulting concentration gradient, result in substantial...

Rezumat: Sănătatea fizică și psihică bună reprezintă indubitabil unele dintre cele mai prețioase calități pe care le poate poseda o persoană. Fără aceste elemente, orice activitate simplă devine un efort iar orice efort devine o imposibilitate. Astfel, o mare parte din populația din România care se prezintă în camera cu gardă cu stare generală alterată dată de hipertensiunea arteriala (HA) rapo...

BACKGROUND Ductal intraepitelial neoplasia (DIN) represents a spectrum of disease that may progress from usual hyperplasia to ductal carcinoma in situ (DCIS) grade 3. The aim of the study was to asses the correlation between the DIN classification and the surgical treatment including sentinel lymph node biopsy (SLNB). PATIENTS AND METHODS In this retrospective study, 229 patients with DIN had...