Automatic lung lesion segmentation of chest computer tomography (CT) scans is considered a pivotal stage toward accurate diagnosis and severity measurement COVID-19. Traditional U-shaped encoder–decoder architecture its variants suffer from diminutions contextual information in pooling/upsampling operations with increased semantic gaps among encoded decoded feature maps as well instigate vanish...

The recent article describing a positive association between serum uric acid and several inflammatory markers in the InCHIANTI study addresses the issue of whether uric acid is an independent cardiovascular risk factor. Uric acid is an antioxidant and appears to contribute to salutary immune reactions, but the cardiovascular significance of rises in its serum level remains poorly understood. I ...

1. In 125 cases of perirenal fat samples derived from human necropsies (from 1 month to 86 years), the occurrence of the brown adipose tissue was examined. Brown fat cells were contained in 72% (90: 125) of the cases. 2. In the infants, all samples contained maximal amounts of brown fat cells: the perirenal fat was composed almost exclusively of brown fat cells: in children and teenagers they b...

When established in culture, human neuroblastoma cell lines typically are comprised of heterogeneous cellular subpopulations, including neuroblastic (N-type), substrate-adherent (S-type), and intermediate (I-type) cells that can be distinguished by their characteristic morphologies and expression of differentiation-associated antigens. Here we examined the relative levels of the Bcl-2 oncoprote...

In adult albino mice the effects of increased intraocular pressure on the outer retina and its circuitry was investigated at intervals ranging 3-14 weeks. Ocular hypertension (OHT) was induced by cauterizing the vessels draining the anterior part of the mice eye, as recently reported (Salinas-Navarro et al., 2009a). Electroretinographic (ERG) responses were recorded simultaneously from both eye...

The recent article describing a positive association between serum uric acid and several inflammatory markers in the InCHIANTI study addresses the issue of whether uric acid is an independent cardiovascular risk factor. Uric acid is an antioxidant and appears to contribute to salutary immune reactions, but the cardiovascular significance of rises in its serum level remains poorly understood. I ...

UNLABELLED The age structure of human populations is exceptional among animal species. Unlike with most species, human juvenility is extremely extended, and death is not coincident with the end of the reproductive period. We examine the age structure of early humans with models that reveal an extraordinary balance of human fertility and mortality. We hypothesize that the age structure of early ...

The effects of acidic precipitation on stream chemistry were measured on an east-central Pennsylvania basin. When combined with flow and chemical mass balances, the data can help quantify hydrological source areas and their contributions to acidic storm hydrographs. For small storms on the well-buffered agricultural basin, small volumes of acidic precipitation falling directly on the stream sur...

BACKGROUND Senescence of the neurons is believed to be a focal factor in the development of age-related neurodegenerative diseases such as Alzheimer's disease. Diminutions in the levels of nerve growth factor (NGF) lead to major declines in brain cell performance. Functional foods, believed to mitigate this deficiency, will be reaching a plateau in the near future market of alternative and prev...

Large pyramidal neurons of rat and human neocortex stain immunohistochemically for phosphate-activated glutaminase (PAG). In a limited number of postmortem brains, we find large reductions in cortical PAG activity in Alzheimer's disease (AD). This finding is consistent with histological evidence that pyramidal neurons are affected in AD. The reductions are greater than those found in the same s...