نتایج جستجو برای: dige

تعداد نتایج: 682  

2017
Jianmin Wang Yingli Liu Lijuan Tang Sufen Qi Yingjun Mi Dianwu Liu Qingbao Tian

The present study aimed to identify candidate substrates of ubiquitin-specific protease (USP)13 using two-dimensional fluorescence difference gel electrophoresis (2D-DIGE). USP13 is a well-characterized member of the USP family, which regulates diverse cellular functions by cleaving ubiquitin from ubiquitinated protein substrates. However, existing studies indicate that USP13 has no detectable ...

Journal: :Molecular & cellular proteomics : MCP 2008
Elizabeth Yohannes Jinsook Chang George J Christ Kelvin P Davies Mark R Chance

Protein expression profiles in rat bladder smooth muscle were compared between animal models of streptozotocin-induced diabetes mellitus (STZ-DM) and age-matched controls at 1 week and 2 months after induction of hyperglycemia with STZ treatment. At each time point, protein samples from four STZ-DM and four age-matched control rat bladder tissues were prepared independently and analyzed togethe...

2013
Thibault Chaze Louis Hornez Christophe Chambon Iman Haddad Joelle Vinh Jean-Philippe Peyrat Marc Benderitter Olivier Guipaud

The finding of new diagnostic and prognostic markers of local radiation injury, and particularly of the cutaneous radiation syndrome, is crucial for its medical management, in the case of both accidental exposure and radiotherapy side effects. Especially, a fast high-throughput method is still needed for triage of people accidentally exposed to ionizing radiation. In this study, we investigated...

Journal: :Ecotoxicology and Environmental Safety 2012

Journal: :Journal of proteome research 2007
Flora Cimmino Daniela Spano Mario Capasso Nicola Zambrano Roberta Russo Massimo Zollo Achille Iolascon

Neuroblastoma (NB) is an infant tumor which frequently differentiates into neurons. We used two-dimensional differential in-gel electrophoresis (2D-DIGE) to analyze the cytosolic and nuclear protein expression patterns of LAN-5 cells following neuronal differentiating agent all-trans-retinoic acid treatment. We identified several candidate proteins, from which G beta2 and Prefoldin 3 may have a...

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