Sir, The anti-convulsant drug carbamazepine may induce generalized exanthema or, less frequently, severe cutaneous eruptions, such as hypersensitivity syndrome or toxic epidermal necrolysis. The development of psoriasiform eruptions and the exacerbation of pre-existing psoriasis have been recognized as common adverse reactions to beta-blockers, lithium and antimalarials (1). Additional causativ...

A 45-year-old healthy female presented to the dermatologic clinic with a 6-month history of diffuse hair loss and thinning but no relevant medical or pharmacological history. Scalp examination showed low-density hair in a diffuse pattern, which was more pronounced in the parietal and frontal areas ( fig. 1 a). The pull test was positive. Scalp dermoscopy revealed hair-shaft thinning and a lot o...

A young adult male patient presented with diffuse hair loss of two years duration. Clinical features and investigations were suggestive of loose anagen hair syndrome. He developed alopecia totalis during follow-up. Scalp biopsy revealed perifollicular lymphocytic infiltration. A diagnosis of adult-onset loose anagen hair syndrome with alopecia areata was made. Introduction Loose anagen hair syn...

Hair loss may accompany several endocrine disorders, including hypopituitarism, hypothyreosis, hyperthyreosis, hypoparathyroidism, diabetes mellitus, growth hormone deficiency, hyperprolactinaemia, polycystic ovary syndrome, SAHA syndrome, congenital adrenal hyperplasia, Cushing syndrome, or virilising tumours. Most patients with endocrine disorders present with diffuse non-scarring alopecia, s...

The hair follicle is a complete mini-organ that lends itself as a model for investigation of a variety of complex biological phenomena, including stem cell biology, organ regeneration and cloning.  The arrector pili muscle inserts into the hair follicle at the level of the bulge- the epithelial stem cell niche.  The arrector pili muscle has been previously thought to be merely a bystander and n...

Hair loss may accompany several endocrine disorders, including hypopituitarism, hypothyreosis, hyperthyreosis, hypoparathyroidism, diabetes mellitus, growth hormone deficiency, hyperprolactinaemia, polycystic ovary syndrome, SAHA syndrome, congenital adrenal hyperplasia, Cushing syndrome, or virilising tumours. Most patients with endocrine disorders present with diffuse non-scarring alopecia, s...

Alopecia areata incognita, also known as diffuse alopecia areata, is a rare form of alopecia areata described predominantly in young women. In cases of alopecia areata incognita, the typical patchy distribution of hair loss in classical alopecia areata is absent, but abrupt and intense hair loss is characteristic. While the clinical picture presented by this disease closely resembles that of te...

Hair loss is a very common complaint. Patients may describe increased shedding and diffuse or localized alopecia. The differential diagnosis of hair loss includes a number of disorders causing cicatricial or noncicatricial alopecias. This paper describes the clinical approaches and diagnostic tests that are useful in the evaluation of patients presenting with alopecia. It also reviews treatment...