Aortic valve and mitral annular calcification are commonly seen in elderly patients with chronic kidney disease and/ or altered calcium hemostasis. Extensive myocardial is rare. We present a case of an female who presented sepsis heart failure on clinical background showed extensive multi-modality imaging, leading to severe impairment systolic diastolic function restrictive physiology.
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We studied a cohort of 1408 older subjects to explore whether postural changes in blood pressure (BP; defined as orthostatic hypo- or hypertension) can predict the onset of cognitive deterioration. Orthostatic hypotension was defined as a drop of 20 mm Hg in systolic or 10 mm Hg in diastolic BP and orthostatic hypertension as a rise of 20 mm Hg in systolic BP. Orthostatic BP values were grouped...

AIMS This study was designed to characterise both the systolic and diastolic mechanical properties of regions with different degrees of myocardial ischaemic injury after reperfused acute myocardial infarction (AMI). METHODS AND RESULTS Fourteen dogs underwent 90-min coronary artery occlusion followed by reperfusion. Image acquisition was performed 24 h after reperfusion using three techniques...

BACKGROUND Impaired left ventricular (LV) diastolic function is a common pathophysiological feature of patients with hypertrophic cardiomyopathy (HCM). High-normal thyrotropin (thyroid-stimulating hormone, TSH) levels may alter the performance of the left ventricle. AIM To ascertain whether the severity of impaired LV diastolic function in HCM patients might worsen with elevating TSH levels w...

To clarify the basis of increased left ventricular (LV) end-diastolic pressure associated with isometric exercise, LV diastolic and systolic function were examined in 25 patients during sustained handgrip. During handgrip, average systemic arterial mean pressure increased by 20 mm Hg, and LV systolic pressure rose by 31 mm Hg, though in five patients, no increase in mean arterial or LV systolic...

Abstract Background The diagnosis of heart failure with preserved ejection fraction (HFpEF) remains challenging. Exercise-stress testing is recommended in case uncertainty; however, this approach time-consuming and costly. Since EF does not represent normal systolic function, we evaluated cardiovascular magnetic resonance (CMR) comprehensive cardiac hemodynamic forces (HDF) analyses for an in-d...

The patient presented by Dr Patricia Campbell1 from the Advanced Heart Disease Section of Brigham and Women’s Hospital exemplifies challenges that surround the possible diagnosis of constrictive pericarditis. Constrictive pericarditis is a pericardial compressive syndrome due to fibrosis, scarring, and occasionally calcification of the pericardium. The primary pathophysiological consequence is ...

AIMS The aim of our study was to evaluate the influence of left ventricular (LV) diastolic filling impairment on postoperative results in patients (pts) with low LV ejection fraction (EF) (<35%) undergoing coronary artery bypass grafting (CABG). METHODS The study covered 56 patients (mean age 58.9 +/- 17.1 years). Two dimensional Doppler echocardiographic investigations were performed pre- an...