The influence of dietary supplementation with dehydroepiandrosterone-sulphate (DHEA-S) at 0.6% was investigated in male Syrian golden hamsters initiated by treatments with azoxymethane(AOM), and dihydroxy-di-n-propyl nitrosamine (DHPN), timed after transfer from a choline-deficient to a normal diet. These carcinogens respectively target the colon, and the respiratory tract, the liver and pancre...

Abstract Background and Aims The onset development of metabolic abnormalities are closely related to polycystic ovary syndrome (PCOS). It has not yet been determined whether PCOS contributes kidney injury, the mechanism underlying condition is fully understood. Treatment with vitamin D shown have beneficial effects on women renal disease. This study investigated hypothesis that supplementation ...

OBJECTIVE To describe a case of dramatically improved ovarian reserve in a 42.7-year-old woman who was using the dietary supplement dehydroepiandrosterone (DHEA) as well as acupuncture. DESIGN Case report. SETTING Private IVF center. PATIENT(S) A 42.7-year-old patient with initial severely decreased ovarian reserve. INTERVENTION(S) Serial ovulation induction with concomitant use of DHEA...

Background Scientific data on the performance of collegiate female tennis players during the menstrual phases are scarce. Trial design Double-blind, counter-balanced, crossover trials were conducted to examine whether tennis performance was affected during menstruation, with and without dehydroepiandrosterone sulfate (DHEA-S) supplementation. Methods Ten Division 1 collegiate tennis players...

BACKGROUND With infertility populations rapidly aging, treatments improving pregnancy chances assume increasing clinical importance. Dehydroepiandrosterone (DHEA) has been reported to improve pregnancy rates and lower miscarriage rates in women with diminished ovarian function. This study was planned to evaluate whether pretreatment with DHEA may improve in vitro fertilization (IVF) parameters ...

Dehydroepiandrosterone (DHEA) and the dehydroepiandrosterone sulfate (DHEA-S) are steroids produced mainly by the adrenal cortex. There is evidence from both human and animal models suggesting beneficial effects of these steroids for obesity, diabetes mellitus, hypertension, and osteoporosis, conditions associated with the post-menopausal period. Accordingly, we hypothesized that DHEA supplemen...

Background: Diminished ovarian reserve (DOR) predicts decreased response to stimulation. Low serum anti-Mullerian hormone (AMH) is associated with DOR. AMH a marker of and acts as predictor stimulation protocol. The up regulated by vitamin D via elements that bind the receptor. Vitamin supplementation has role in increasing AMH. objective was compare combined effect DHEA vs alone on Methods: Th...

The hydroxylation of dehydroepiandrosterone (DHEA) to 7? -hydroxy-5-androstene-17-one (7?-OH-DHEA) and 7?-hydroxy-5-androstene-17-one (7?-OH-DHEA) by Gibberella sp. CICC 2498 Absidia coerulea 41050 was investigated. media ingredients were optimized. Single factors such as the DHEA concentration, culture time, medium volume, inoculum rate individually investigated generate optimum biotransformat...

EWA OLECH, MD Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation; Clinical Assistant Professor, University of Oklahoma Health Sciences Center, Oklahoma City JOAN T. MERRILL, MD* Head, Clinical Pharmacology Research Program, Oklahoma Medical Research Foundation, and Professor of Medicine, Oklahoma Health Sciences Center, Oklahoma City; Medical Director, Lupus Foundation...