357 Corneal transplantation has been widely performed since the first successful surgery was described by Zirm. Recent data from the Eye Bank Association of America (EBAA), the accredited organization that tracks donor quality and volume of surgeries performed anually in the United States, has shown that 46,253 corneal tissues were used for transplantation in 2014 domestically while 76,431 tiss...

The cornea remains in a state of deturgescence, maintained by endothelial cell Na+/K+ ATPase and by tight junctions between endothelial cells that limit entrance of fluid into the stroma. Fuchs' endothelial corneal dystrophy (FECD) was initially described by Fuchs in 1910 as a combination of epithelial and stromal edema in older patients. It manifests as bilateral, albeit asymmetric, central co...

We report a case series of three patients with previous trabeculectomies who developed elevated intraocular pressure (IOP) in the immediate postoperative period after routine Descemet stripping automated endothelial keratoplasty (DSAEK). All patients had functioning trabeculectomies preoperatively, and developed elevated IOP between 41 and 69 mm Hg within 24 hours following DSAEK surgery. The I...

D escemet membrane endothelial keratoplasty (DMEK), the newest and most advanced form of endothelial transplantation, represents the culmination of the evolution of keratoplasty techniques. It has nudged aside its predecessor, Descemet stripping automated endothelial keratoplasty (DSAEK), just as DSAEK displaced its own forerunner, deep lamellar endothelial keratoplasty (DLEK). What differentia...