The aim of the present study was to investigate anti fungal activities of the fresh extract of Allium ascalonicum Linn. (Liliaceae) against clinically important yeast, dermatophytes and some saprophytic fungi in vitro. The anti fungal effects of fresh crude juice of shallot were determined against 11 isolates of Candida albicans, three species of dermatophytes (Microsporum gypseum, Trichophyton...

A total of 134 clinical samples such as hair plucks and skin scrapings were collected from dogs with cutaneous lesions of alopecia, hyperpigmentation, and scales. A part of clinical material was directly examined under microscope after digestion with 10% potassium hydroxide. The remaining material was cultured in Sabouraud‘s Dextrose agar to study the presence of fungi based on the colony morph...

OBJECTIVE Urea is commonly used as a keratolytic substance in the treatment of onychomycoses to improve the penetration of antifungal drugs in the lesion sites. The aim of the present study was to investigate the inhibitory action of urea on samples of dermatophytes in vitro. METHOD Minimum inhibitory concentration of urea was determined for 31 samples of dermatophytes cultured in Sabouraud-d...

Several human skin diseases and disorders are associated with two groups of fungi, the dermatophytes and Malassezia. Although these skin-related problems are not generally life threatening, they are among the most common diseases and disorders of mankind. These fungi are phylogenetically divergent, with the dermatophytes within the Ascomycota and Malassezia within Basidiomycota. Genome analysis...

Skin mycoses are caused mainly by dermatophytes, which are fungal species that primarily infect areas rich in keratin such as hair, nails, and skin. Significantly, there are increasing rates of antimicrobial resistance among dermatophytes, especially for Trichophyton rubrum, the most frequent etiologic agent worldwide. Hence, investigators have been developing new therapeutic approaches, includ...

Anteaters comprise three different species: Myrmecophaga tridactyla (flag anteater), Tamandua tetradactyla (mini anteater) and Cyclopes didactylus (anteater), some considered vulnerable to extinction. These species are distributed over a large part of the Brazilian territory, especially in cerrado biome. In order preserve these species, research work on health status animals has been carried ou...

Objective: The study was to evaluate the antidermatophytic activity of the ethanol, ethyl acetate and hexane extract of Neem ( Azadirachta indica) leaves against dermatophytes isolated from patients with dermatophytosis. Methods: Clinical samples from 200 patients were subjected to (KOH) examination and culture isolation. Causative agents were identified macroscopically and microscopically. The...

The causative agents of skin infection are bacteria, fungi and in specific dermatophytes. Many infectious diseases have been treated with plant extracts. The free and bound flavonoids fractions of Wrightia tinctoria (Roxb) R.Br. (Apocynaceae), leaves were tested against 10 bacterial, 3 fungal and 4 dermatophytic strains affecting the skin using disc diffusion and broth micro dilution method. Th...

The essential oil and the aqueous, hexane and methanolic fractions from Hyptis ovalifolia leaves were evaluated for their antifungal activity in vitro against 60 strains of dermatophytes: 10 strains of Microsporum canis, 10 of M. gypseum, 20 of Trichophyton rubrum and 20 of T. mentagrophytes. The extracts inhibited growth of the dermatophytes tested at different concentrations. The most biologi...

Dermatophytes are keratinolytic fungi responsible for a wide variety of diseases of the skin, nails and hair of mammals. Their identification is often complicated, labor-intensive and time consuming due to the high degree of intra-species morphological similarity, and also requires scientific knowledge and practice. The aim of this study was to demonstrate that MALDI-TOF MS technique may be a f...