been reported in the world literature.4 The cutaneous pigmentation commonly involves the ophthalmic, maxillary, and occasionally the mandibular division of the trigeminal nerve. Oculodermal melanocytosis occurs most often in orientals and blacks and is rarely seen in the white population.2 5-7 In contrast, malignant melanoma transformation associated with ODM and OM is known to occur more often...

Esophageal melanocytosis is a rare but benign clinicopathologic entity, often presenting incidentally, with reported incidence in 0.07% to 2.1% of gastrointestinal endoscopies. It characterised by non-atypical melanocytic proliferation and increased melanin deposition the esophageal mucosa. We report 71-year-old female who underwent oesophagogastroduodenoscopy for progressive 1-year history dys...

Neurocutaneous melanosis (NCM) is a rare congenital disorder characterized by the association of large and/or multiple congenital melanocytic nevi (CMN) of the skin with melanocytic lesions of the leptomeninges, including melanocytosis. Leptomeningeal melanocytosis carries a poor prognosis once neurological symptoms develop. Despite surgery, which is often not radical, few other treatment optio...

Oculodermal melanocytosis (ODM) is a congenital melanocytic hyperpigmentation of the face and ocular tissues. The eponym naevus of Ota as described by Otal has been used interchangeably with ODM and ocular melanosis (OM) in many reported cases. The original definition by Ota included patients with and without ocular involvement. For these reasons, we will refer to the term oculodermal melanocyt...

INTRODUCTION Primary melanocytosis of the leptomeninges is a rare tumor, most likely originating from the melanocytes in the leptomeninges. The average survival is only about 5 months. CASE REPORT A 61-years-old woman presented with headache, amaurosis and hallucinations lasted for two months, and she had been treated at the Clinic for Psychiatry and Clinic for Infectious Diseases. The cerebr...

To cite: Musumeci ML, Lacarrubba F, Santagati C, et al. BMJ Case Rep Published online: [please include Day Month Year] doi:10.1136/bcr-2013200740 DESCRIPTION A 3-week-old Asian male newborn (42 weeks gestation, normal spontaneous vaginal delivery) presented for evaluation of multiple congenital greyish-blue macules. Dermatological examination showed a large grey to light-grey patch with undefin...

RATIONALE Primary malignant melanoma of the esophagus (PMME) is a rare disease with an extremely poor prognosis. In contrast, melanocytosis is a benign condition defined as melanocytic proliferation with melanin deposition. PMME is often accompanied by melanocytosis, but differentiating between them is difficult because of their similar appearance. PATIENT CONCERNS Here, we reported 3 PMME ca...