Articles about the development of derivative spectrophotometric methods and analytical applications of derivative spectrophotometry (DS) published in the last nine years (since 1994) are reviewed.

in this study, different derivative spectrophotometric methods are proposed for the simultaneous determination of chlorpheniramine maleate (cp), phenylephrine hcl (pe) and phenylpropanolamine hcl (pp) in their ternary mixtures and in pharmaceutical dosage forms. spectra of single component and ternary mixtures of various concentrations and combinations from zero- to fourth-derivation were obtai...

In this study, zero-, first-, secondand third-order derivative spectrophotometric methods were developed for quantitave determination of atenolol in pharmaceutical preparation. In zero order spectrophotometry, absorbance values were measured at 276 nm in zero order spectra of solution of atenolol in methanol in the range of 245-310 nm. In first derivative spectrophotometry, absorbance values we...

The interaction of human serum albumin with Ethyl 2-[2-(dimethylamino)-4-(4-nitrophenyl)- 1,3-thiazole-5-yl]-2-oxoacetate was investigated by using isothermal titration UV-visible spectrophotometry in tris-buffer, pH 7.4. According to these results, it was found that there are a set of 4 binding sites for this ligand on HSA with positive cooperativity in the binding process. This thiazole deriv...

Theoretical aspects, instrumental devices and analytical applications of derivative ultraviolet-visible region absorption spectrophotometry are reviewed.

resolution of binary mixtures of theophylline (theo), montelukast (mkst) and loratadine (lora) with minimum sample pretreatment and without analyte separation has been successfully achieved by multivariate spectrophotometric calibration, together with partial least-squares (pls-1), principal component regression (pcr) and hybrid linear analysis (hla). data of analysis were obtained from uv–vis ...