Aim: To design an accommodating intraocular lens with extended accommodative range that can be adapted to current standard phacoemulsification and endocapsular implantation technique. Method: Ray tracing analysis and lens design; cadaver eye implantation. Results: Ray tracing analysis indicated that axial movement of an exaggerated converging anterior optic linked by spring loaded haptics to a ...

The three-dimensional structure of the stacked-disk rod of tobacco mosaic virus protein has been recon­ structed to a resolution of about 2 nm from electron microscope images. Closed rings of seventeen protein subunits (compared with 16^ in one turn of the virus helix) are stacked in polar fashion, the stacking being accompanied by an axial perturbation of periodicity 5.3 nm connecting successi...

Movement coordination between opposite body sides relies on neuronal circuits capable of controlling muscle contractions according to motor commands. Trunk and limb muscles engage in distinctly lateralized behaviors, yet how regulatory spinal circuitry differs is less clear. Here, we intersect virus technology and mouse genetics to unravel striking distribution differences of interneurons conne...

The three-dimensional structure of the stacked-disk rod of tobacco mosaic virus protein has been recon­ structed to a resolution of about 2 nm from electron microscope images. Closed rings of seventeen protein subunits (compared with 16^ in one turn of the virus helix) are stacked in polar fashion, the stacking being accompanied by an axial perturbation of periodicity 5.3 nm connecting successi...

purpose: to evaluate the effect of childhood corneal opacity on the anteroposterior length of the globe in adulthood. methods: twenty-three patients with significant unilateral corneal opacity which had developed before the age of 6 years and the normal fellow eyes (controls) were evaluated. a comprehensive ocular examination including measurement of anterioposterior length and anterior chamber...

The role of axial form and function during the vertebrate water to land transition is poorly understood, in part because patterns of axial movement lack morphological correlates. The few studies available from elongate, semi-aquatic vertebrates suggest that moving on land may be powered simply from modifications of generalized swimming axial motor patterns and kinematics. Lungfish are an ideal ...

Airway surface liquid is comprised of mucus and an underlying, watery periciliary liquid (PCL). In contrast to the well-described axial transport of mucus along airway surfaces via ciliary action, theoretical analyses predict that the PCL is nearly stationary. Conventional and confocal microscopy of fluorescent microspheres and photoactivated fluorescent dyes were used with well-differentiated ...

Airway surface liquid is comprised of mucus and an underlying, watery periciliary liquid (PCL). In contrast to the well-described axial transport of mucus along airway surfaces via ciliary action, theoretical analyses predict that the PCL is nearly stationary. Conventional and confocal microscopy of fluorescent microspheres and photoactivated fluorescent dyes were used with well-differentiated ...