Inherited dentin defects are classified into three types of dentinogenesis imperfecta (DGI) and two types of dentin dysplasia (DD). The genetic etiology of DD-I is unknown. Defects in dentin sialophosphoprotein (DSPP) cause DD type II and DGI types II and III. DGI type I is the oral manifestation of osteogenesis imperfecta (OI), a systemic disease typically caused by defects in COL1A1 or COL1A2...

Hereditary defects of dentin include dentinogenesis imperfecta (DGI) and dentin dysplasia (DD). They are characterized by abnormal dentin for­ mation. Within the last 32 years, since the first classification system was pro­ posed, significant advances have been made regarding their genetic aetio­ logies. In the classification system suggested by Shields et al (1973), den­ tinogenesis imperfecta...

The effects of dietary sucrose and systemic glucocorticoid treatment on the response of the pulpodentinal complex to dental caries were examined in an experimental rat model. The possible role of dentinal caries on dentin formation was also examined. After 5-6 weeks of a dietary and/or medication period, the areas of dentin formation and dentinal caries were quantified in the molars of growing ...

OBJECTIVE The effect of dentin desensitizer Systemp on the shear bond strength of composite resin to dentin using three different bonding agents, i.e., Prime & Bond NT, Xeno V+, and Futurabond DC were evaluated. MATERIALS AND METHODS Sixty recently extracted human premolars were divided into six groups of ten teeth each. The superficial dentin was etched with 37% phosphoric acid. In Groups I,...

The relationship between clinical characteristics of carious dentin and bacterial colonization after partial caries removal is not completely understood. The aim of this study was to compare microbial counts between categories of carious dentin color, consistency and humidity, and to evaluate the correlation between these characteristics and the presence of cariogenic microorganisms in deep cav...

Dentin sialophosphoprotein (Dspp) is critical for proper dentin biomineralization because genetic defects in DSPP cause dentin dysplasia type II and dentinogenesis imperfecta types II and III. Dspp is processed by proteases into smaller subunits; the initial cleavage releases dentin phosphoprotein (Dpp). We incubated fluorescence resonance energy transfer (FRET) peptides containing the amino ac...