INTRODUCTION Hypodontia, agenesis of one or of more teeth, is a common developmental dental anomaly. To date, over 200 candidate genes have been demonstrated to be active in tooth development. The genes Pax9 plays an important role in the initial stage of odontogenesis. Mutations of Pax9 are associated with autosomal dominant forms of oligodontia, the agenesis of more than six teeth and occasio...

Agenesis of the paranasal sinuses is an uncommon clinical condition that appears mainly in the frontal (12%) and maxillary (5-6%) sinuses; in some populations, it appears at a higher proportion. This study investigated the prevalence of agenesis of the frontal sinuses using dental volumetric tomography (DVT) in Turkish individuals. The frontal sinuses of 410 patients were examined by DVT scans ...

OBJECTIVES The aim of this study was to investigate the prevalence of maxillary lateral incisor (MLI) agenesis and associated dental anomalies as well as skeletal patterns in an orthodontic population, and then to compare it with the prevalence of these anomalies in the general population. STUDY DESIGN The material of the present study included the records of the 3872 orthodontic patients. Th...

The aim of this study was to establish teeth number anomalies in relation to gender, tooth type, location, distribution pattern and the association between frequently missing teeth among a group of dental patients in Turkey. A total of 378 non-syndromic patients (240 females and 138 males) with an age range of 7-45 (x +/- SD = 22.07 +/- 3.6) having evidence of absent or excess teeth were evalua...

Increasing lower dental arch crowding with the age is a recognized clinical problem, and one that has become more apparent in recent years as more adults retain their teeth longer. One of the theories is that the erupting third molars push anterior teeth forward and cause their crowding. On the other hand, a number of studies found no correlation between lower third molars and lower incisor cro...

We investigated the association between polymorphisms in the MMP2 (rs243865), MMP9 (rs17576), and MMP13 (rs2252070) genes with tooth agenesis in humans. Two hundred eighty-five unrelated individuals (202 controls without tooth agenesis and 83 cases with tooth agenesis) were evaluated in a cross-sectional single-center study. The study participants were recruited through the Pediatric Dental Cli...

Introduction: Hypodontia is one of the most prevalent craniofacial anomalies worldwide. Malocclusion could be prevented, by early treatment of this anomaly. The aim of the present study was to investigate the prevalence of congenital missing tooth (hypodontia) in patients, referred to Orthodontic Department of Kerman Dental School, as well as other private Dental Care centers. Methods: In this...

Dental agenesis is a commonly encountered dental anomaly that affects more than 20% of the human population. It can be categorized as hypodontia, oligodontia, or anodontia. Oligodontia occur either an isolated finding part syndrome, and causative factor environmental genetic. : This report describes three cases isolated, non-syndromic tooth with single/ multiple missing permanent teeth. No othe...

BACKGROUND Even though tooth agenesis is the most common developmental anomaly of the human dentition, its genetic background and pathogenic mechanism(s) still remain poorly understood. Syndromic and isolated forms of hypodontia have been described and can occur sporadically or in families. OBJECTIVES We describe and analyse the hypo-/oligodontia phenotype variations in families. The index pa...

BACKGROUND The congenital absence of one or more teeth is a dental anomaly that frequently occurs in the world's population with a wide variability of distribution. The aim of this study is to assess the current prevalence of dental agenesis in the permanent dentition (excluding third molars) using a sample of Italian orthodontic patients. METHODS Panoramic radiographs of 4006 Caucasian child...