Germinal centers (GCs) are complex, multicell-type, transient structures that form in secondary lymphatic tissues in response to T cell-dependent stimulation. This process is crucial to the adaptive immune response because it is the source of affinity maturation and long-lived B cell memory. Our previous studies showed that the growth of murine splenic GCs is nonsynchronized, involving broad-vo...

Abstract The Cretaceous Cordilleran foreland basin strata exposed in the Book Cliffs of eastern Utah and western Colorado have motivated important concepts linking thrust belt deformation evolution largely on basis sequence stratigraphy, stratal architecture, sediment provenance evolution. However, these methods approaches generally cannot provide critical insights into temporal or causal linka...

The material characteristics such as size effect are one of the most important factors that could not be neglected in cutting the material at nanoscale. The effects of anisotropic nature of single crystal materials in nano-cutting are investigated employing the molecular dynamics simulation. Results show that the size effect of the plastic deformation is based on different plastic carriers, suc...

Objective(s): Diazinon (DZ) is an organophosphate pesticide that induces oxidative damage in different organs. The aim of this study was to compare the effectiveness of nanomicelles containing curcuminoids (NCUR) and natural curcumin (CUR) in attenuating the oxidative damage induced by DZ in male rats. Materials and Methods: After a single intraperitoneal (IP) injection of DZ (100 mg/kg), the r...

Our research is concerned with the modeling and design of semantically-enabled, efficient, safe and performant cyber-physical transportation systems (CPTS). As a class of cyber-physical systems (CPS), CPTS are characterized by a tight integration of software and physical processes for smartness, increased performance, safety and management of system functionality. We adopt this perspective in o...

A study has been made of the deformation field in plane-strain indentation of metals with a flat punch. Deformation field parameters such as velocity and strain rate have been measured using the technique of particle image velocimetry. For this purpose, images of the indentation region were recorded in situ during the deformation process, and motion of ‘asperities’ specially introduced onto a s...

Olfactory sensory axons target well-defined intermediate targets in the zebrafish olfactory bulb called protoglomeruli well before they form odorant receptor-specific glomeruli. A subset of olfactory sensory neurons are labeled by expression of the or111-7:IRES: GAL4 transgene whose axons terminate in the central zone (CZ) protoglomerulus. Previous work has shown that some of these axons mispro...