Polygonum multiflorum is a traditional Chinese medicine with a long history in hair growth promotion and hair blackening. The purpose of the study was to examine the effect and the mechanism of Polygonum multiflorum in hair blackening. C57BL/6 mice hair fade was induced with H2O2 and used in this research. Hair pigmentogenesis promotion activities of Polygonum Multiflorum Radix (PMR, raw crude ...

We previously demonstrated that whole hair follicles could be cryopreserved to maintain their stem-cells differentation potential. In the present study, we demonstrated that cryopreserved mouse whisker hair follicles maintain their hair growth potential. DMSO better cryopreserved mouse whisker follicles compared to glycerol. Cryopreserved hair follicles also maintained the hair follicle-associa...

Objective: Pumpkin (Cucurbita pepo L.) seed oil mainly consists of saturated and unsaturated fatty acids. Previously, it was reported that oral administration of pumpkin seed oil (PSO) improved hair growth in male pattern alopecia. This study aimed to evalua...

Background: (AGA) is a very common hair disorder in men, Topical minoxidil and more recently low-level light therapy Platelet-rich plasma have been used the management of (AGA). Objectives: To assess Trichogenic effect LLLT combined with PRP AGA. Patients methods: Forty seven patients AGAwere subjected to plus LLLT, affected area all were treated for three months then follow up another months. ...

Androgenetic alopecia (AGA) is a hereditary, androgendependent dermatological disorder more common in men. It is occasionally seen in women. It commonly begins by 20 years of age and affects nearly 50% of men by the age of 50 years [1]. It is a progressive thinning of the scalp hair in a defined pattern causing significant lowering of the self esteem and psychological well being of the patient....

Purpose: To investigate the effect of Glycyrrhiza glabra root extract on hair growth in female Wistar rats. Methods: Female Wistar rats were used for the hair growth promotion studies. They were divided into three groups(n = 6) and their dorsal skin was completely denuded to completely remove hair. Paraffin oil (control), 2 % minoxidil solution (reference) or petroleum ether (60 – 80 C) root ex...

β-Catenin, a key transducer molecule of Wnt signaling, is required for adult hair follicle growth and regeneration. However, the cellular source of Wnt ligands required for Wnt/β-catenin activation during anagen induction is unknown. In this study, we genetically deleted Wntless (Wls), a gene required for Wnt ligand secretion by Wnt-producing cells, specifically in the hair follicle epithelium ...

Biota orientalis L. leaf extract (BOLE) is used medically to improve strength and arrest hemorrhage. In China, BOLE has been used in traditional medicine for its antibacterial properties and for hair restoration. In this study, we investigated the mechanism of hair restoration by BOLE from the point of view of the sebum suppressant effect and hair loss prevention. BOLE at 25 or 50 μg/mL final c...