Rapidly developed de novo aneurysm is very rare. We present a rapidly developed and ruptured de novo anterior communicating aneurysm 8 days after the rupture of another aneurysm. This de novo aneurysm was not apparent in the initial 3-dimensional computed tomography and digital subtraction angiography. We reviewed the literature and discussed possible mechanisms for the development of this de n...

BACKGROUND De novo malignancies occur after liver transplantation because of immunosuppression and improved long-term survival. But the spectrums and associated risk factors remain unclear. AIMS To describe the overall pattern of de novo cancers in liver transplant recipients. METHODS Data from Scientific Registry of Transplant Recipients from October 1987 to December 2009 were analyzed. Th...

1 Probabilistic model of de novo mutations and inherited variations in family data 2 2 The impact of mutation rates on the Multiplicity Test 3 3 Bayesian inference of risk genes 3 4 Estimation of the prior parameters by the Hierarchical Bayes method 5 5 TADA for multiple types of mutations 5 6 Method of moment estimation of the number of ASD genes and their relative risks 6 7 Comparison with an...

histoid leprosy (hl) is a rare variant of lepromatous leprosy, occurring in long-standing cases, mostly in a background of acquired drug resistance. patients usually present with sudden onset multiple nodules and plaques, most often involving the skin and subcutaneous tissue of trunk and lower limbs. here we report an unusual case of de novo (without any history of prior anti-leprotic therapy) ...

Coffin-Lowry syndrome (CLS) is an X-linked disorder, which affects hemizygous males more severely than females. It is characterized by mental retardation, short stature, head and facial abnormalities, skeletal anomalies and developmental delays. The signs and symptoms vary in different people. We report a 14-year-old male patient, diagnosed with CLS based on his clinical features. Genetic testi...

PURPOSE The aim of this study was to investigate the role of de novo glutamine (Gln) synthesis in the proliferation of C6 glioma cells and its detection with (13)N-ammonia. METHODS Chronic Gln-deprived C6 glioma (0.06C6) cells were established. The proliferation rates of C6 and 0.06C6 cells were measured under the conditions of Gln deprivation along with or without the addition of ammonia or ...

background: translocations involving x chromosome and an autosome are rather rare due to associated infertility in men and subfertility in women. x chromosome translocations are frequently associated with primary or secondary amenorrhea. in this report, a case of primary amenorrhea with a de novo balanced reciprocal translocation was presented between chromosomes x and 1. case presentation: a 2...

in farming activities, various resources and inputs are utilized to produce agricultural products.. one of the most important goals of agricultural managers and programmers is to assess the optimal resource allocation for designing an appropriate cultivation pattern. mathematical programming is a common approach to achieve the optimal pattern. in this study, the two approaches of fuzzy de-novo ...

We show that within the same age cohort, growth rates of young firms are strongly increasing in firm size. This robust empirical pattern is confined to the initial years after entry; growth rates become independent of size as a cohort matures, as predicted by Gibrat’s law of proportionate growth. Both the initial pattern and the subsequent convergence are consistent with the framework of the pa...

We establish a variety of combinatorial bounds on the tradeoos inherent in reconstructing strings using few rounds of a given number of substring queries per round. These results lead us to propose a new approach to sequencing by hybridization (SBH), which uses interaction to dramatically reduce the number of oligonucleotides used for de novo sequencing of large DNA fragments, while preserving ...