نتایج جستجو برای: dbh

تعداد نتایج: 1627  

Journal: :The Journal of pharmacology and experimental therapeutics 2013
Daniel F Manvich Lauren M DePoy David Weinshenker

Inhibitors of dopamine β-hydroxylase (DBH), the enzyme that converts dopamine (DA) to norepinephrine (NE) in noradrenergic cells, have shown promise for the treatment of cocaine abuse disorders. However, the mechanisms underlying the beneficial effects of these compounds have not been fully elucidated. We used the drug discrimination paradigm to determine the impact of DBH inhibitors on the int...

Journal: :Hypertension 1984
T H Joh E E Baetge D J Reis

We have postulated that the catecholamine-synthesizing enzymes tyrosine hydroxylase (TH), dopamine beta-hydroxylase (DBH), and phenylethanolamine N-methyltransferase (PNMT) are coded for by similar genes. To analyze the structural relationship of genes coding for these enzymes, we have cloned DNAs complementary (cDNA) to DBH and PNMT messenger RNAs (mRNAs). Using hybrid selection analysis to id...

2009
M.Z.A. Rahman

This paper presents a new method for individual tree measurement from Airborne LiDAR data. This method involves 3 steps; 1) individual tree crown delineation based on density of high points (DHP), 2) tree filtering, and 3) measurement of tree trunk diameter at breast height (DBH). In the second step, a special tree filtering algorithm is introduced which combines a histogram analysis and region...

2012
Raja Parasuraman Ewart de Visser Ming-Kuan Lin Pamela M. Greenwood

Computerized aiding systems can assist human decision makers in complex tasks but can impair performance when they provide incorrect advice that humans erroneously follow, a phenomenon known as "automation bias." The extent to which people exhibit automation bias varies significantly and may reflect inter-individual variation in the capacity of working memory and the efficiency of executive fun...

Journal: :The Journal of neuroscience : the official journal of the Society for Neuroscience 1999
P Szot D Weinshenker S S White C A Robbins N C Rust P A Schwartzkroin R D Palmiter

Several lines of evidence suggest that norepinephrine (NE) can modulate seizure activity. However, the experimental methods used in the past cannot exclude the possible role of other neurotransmitters coreleased with NE from noradrenergic terminals. We have assessed the seizure susceptibility of genetically engineered mice that lack NE. Seizure susceptibility was determined in the dopamine beta...

2012
Suvi T. Ruohonen Laura H. Vähätalo Eriika Savontaus

Neuropeptide Y (NPY) is a neurotransmitter associated with feeding and obesity. We have constructed an NPY transgenic mouse model (OE-NPY(DBH) mouse), where targeted overexpression leads to increased levels of NPY in noradrenergic and adrenergic neurons. We previously showed that these mice become obese on a normal chow. Now we aimed to study the effect of a Western-type diet in OE-NPY(DBH) and...

Journal: :MCFNS 2009
Thomas Brandeis KaDonna C. Randolph Mike R. Strub

Regression models to predict diameter at breast height (DBH) as a function of tree height and maximum crown radius were developed for Caribbean forests based on data collected by the U.S. Forest Service in the Commonwealth of Puerto Rico and Territory of the U.S. Virgin Islands. The model predicting DBH from tree height fit reasonably well (R2 = 0.7110), with strongest in subtropical moist and ...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 2004
John F Cryan Olivia F O'Leary Sung-Ha Jin Julie C Friedland Ming Ouyang Bradford R Hirsch Michelle E Page Ashutosh Dalvi Steven A Thomas Irwin Lucki

Mice unable to synthesize norepinephrine (NE) and epinephrine due to targeted disruption of the dopamine beta-hydroxylase gene, Dbh, were used to critically test roles for NE in mediating acute behavioral changes elicited by different classes of antidepressants. To this end, we used the tail suspension test, one of the most widely used paradigms for assessing antidepressant activity and depress...

Journal: :Arteriosclerosis, thrombosis, and vascular biology 2008
Dermot F Reilly Anne M Curtis Yan Cheng Elizabeth J Westgate Radu D Rudic Georgios Paschos Jacqueline Morris Ming Ouyang Steven A Thomas Garret A FitzGerald

OBJECTIVE The incidence of heart attack and stroke undergo diurnal variation. Molecular clocks have been described in the heart and the vasculature; however it is largely unknown how the suprachiasmatic nucleus (SCN) entrains these peripheral oscillators. METHODS AND RESULTS Norepinephrine and epinephrine, added to aortic smooth muscle cells (ASMCs) in vitro, altered Per1, E4bp4, and dbp expr...

Journal: :Mathematical biosciences 2014
Rafał Podlaski Francis A Roesch

In recent years finite-mixture models have been employed to approximate and model empirical diameter at breast height (DBH) distributions. We used two-component mixtures of either the Weibull distribution or the gamma distribution for describing the DBH distributions of mixed-species, two-cohort forest stands, to analyse the relationships between the DBH components, age cohorts and dominant spe...

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