Background and Aims: Oncolytic reoviruses can infect and kill malignant cells while sparing their normal counterparts. Reoviral infection can induce or activate autophagy, even though metformin can induce autophagy. Identifying and regulating the cellular pathways important for reovirus replication and oncolysis can improve targeted-biological therapies for cancer. Here, the autophagic process ...

General Structured Voting is a general framework for a wide range of data replication and distributed mutual exclusion schemes. It allows an easy tailoring for speciic objects and environments in a homogeneous manner. In this paper we investigate the characteristics of a so-called voting structure used by General Structured Voting to derive sets of cooperating nodes. Such a set of cooperating n...

In principle, WAN data replication also covers the distribution and replication of plain files. These issues are traditionally handled by wide-area distributed file systems such as AFS [11] and NFS [3, 12], which are both widely used. These distributed file systems aim at shielding data distribution from applications, i.e., they aim at providing a high degree of distribution transparency. As su...

Data replication is a practical and effective method to achieve efficient and fault-tolerant data access in grids. Traditionally, data replication schemes maintain an entire replica in each site where a file is replicated, providing a read-onlymodel. These solutions require huge storage resources to store thewhole set of replicas and do not allow efficient data modification to avoid the consist...

Abstract. Multilab replication projects such as Registered Replication Reports (RRR) and Many Labs are used to replicate an effect in different labs. Data of these usually analyzed using conventional meta-analysis methods. This is certainly not the best approach because it does make optimal use available data a summary rather than participant analyzed. I propose analyze multilab with individual...