BACKGROUND Catha edulis Forsk. (Khat) is used for its psychoactive effects among people in Africa and the Arabian Peninsula, although its utilization is illegal in some countries such as Saudi Arabia. This study examined the pattern of Khat use and assessed the applicability of the Drug Abuse Screening Test-10 (DAST-10) to measure Khat dependence. METHODS A pretested questionnaire was used to...

Ensuring the overall end-user experience is a challenging task in arbitrary style transfer (AST) due to subjective nature of quality. A good practice provide users many instead one AST result. However, existing approaches require run multiple models or inference diversified (DAST) solution times, and thus they are either slow speed limited diversity. In this paper, we propose novel ensuring bot...

Selectively 6-fluorinated analogs of the tumor-associated T(N) antigen Fmoc-Thr(α-O-GalNAc)-OtBu can be efficiently prepared using DAST-mediated de(hydr)oxyfluorination reactions of preformed and orthogonally protected glycosyl amino esters without affecting the labile protecting groups and O-glycosidic linkages. The resulting mono- and difluorinated T(N) analogs are interesting building blocks...

Identification of protein families is a computational biology challenge that needs efficient and reliable methods. Here we introduce the concept of dominance and propose a novel combined approach based on Distance Alignment Search Tool (DAST), which contains an exact algorithm with bounds. Our experiments show that this method successfully finds the most similar proteins in a set without solvin...

Accurate solar photovoltaic (PV) power forecasting is an essential tool for mitigating the negative effects caused by the uncertainty of PV output power in systems with high penetration levels of solar PV generation. Weather classification based modeling is an effective way to increase the accuracy of day-ahead short-term (DAST) solar PV power forecasting because PV output power is strongly dep...

Based on a literature precedent, preparation of methyl 4-azido-3,4,6-trideoxy-3-fluoro-alpha-D-mannopyranoside (18) was attempted via fluorination of methyl 4-azido-2-O-benzyl-4,6-dideoxy-alpha-D-altropyranoside with diethylaminosulfur trifluoride (DAST). Contrary to expectations, the reaction took place with retention of configuration at the site of the fluorination yielding methyl 4-azido-2-O...

INTRODUCTION We examined the prevalence of substance use disorders among homeless and vulnerably housed persons in three Canadian cities and its association with unmet health care needs and access to addiction treatment using baseline data from the Health and Housing in Transition Study. METHODS In 2009, 1191 homeless and vulnerably housed persons were recruited in Vancouver, Toronto, and Ott...