نتایج جستجو برای: das28

تعداد نتایج: 1719  

Journal: :International journal of clinical and experimental medicine 2015
Xiao-Han Cai Shu-Ping Yang Hao-Lin Shen Li-Qing Lin Rong Zhong Rui-Ming Wu Guo-Rong Lv

OBJECTIVE To investigate diagnostic value of ultrasonography scores (US) and contrast-enhanced ultrasonography (CEUS) in evaluating rheumatoid arthritis (RA) activity. METHODS 39 patients with RA were included and the metacarpophalangeal, proximal interphalangeal, wrist, elbow and knee joints of them were examined by high frequency ultrasound. The severe joints and the related indexes (synovi...

2009
Kimme L. Hyrich Chris Deighton Kath D. Watson Deborah P. M. Symmons Mark Lunt

OBJECTIVES Anti-TNF therapy has improved outcomes for patients with highly active RA. Less is known about its effectiveness in patients with lower disease activity. The aim of this analysis is to compare the response to anti-TNF therapy between RA patients with high (DAS28 > 5.1) and moderate (DAS28 > 3.2-5.1) disease activity. METHODS A total of 4687 anti-TNF and 344 DMARD patients with high...

Journal: :Rheumatology 2015
Fernando M Martins José António Pereira da Silva Maria José Santos Elsa Vieira-Sousa Cátia Duarte Helena Santos José António Costa Fernando M Pimentel-Santos Inês Cunha Luís Cunha Miranda Teresa Nóvoa Margarida Cruz Miguel Bernardes Domingos Araujo José Alberto Pereira Silva José Canas Silva Jaime Cunha Branco José António Melo Gomes Augusto Faustino João Eurico Fonseca Helena Canhão

OBJECTIVES . The 28-joint DAS (DAS28), clinical disease activity index (CDAI) and simplified disease activity index (SDAI) are indices frequently used to assess disease activity in RA patients. Cut-off values were defined to classify the states of RA disease activity: remission, low, moderate and high. The aim of this work was to assess disease activity states classified by DAS28, CDAI and SDAI...

2017
M Schoels F Alasti J S Smolen D Aletaha

BACKGROUND Stringent remission criteria are crucial in rheumatoid arthritis (RA) assessment. Disease activity score in 28 joints (DAS28)-remission has not been included among American College of Rheumatology/European League Against Rheumatism definitions, because of its association with significant residual disease activity, partly due to high weighting of acute-phase reactants (APR). New, more...

Journal: :Seminars in arthritis and rheumatism 2011
Chris Pease Janet E Pope Don Truong Claire Bombardier Jessica Widdifield J Carter Thorne Boulos Paul Haraoui Eliofotisti Psaradellis John Sampalis Ashley Bonner

OBJECTIVE Characteristics of Canadian RA patients started on anti-tumor necrosis factor (TNF) treatment were compared with 12 other countries. METHODS Data from the Optimization of HUMIRA trial (OH) were compared with Canadian real world studies [Ontario Biologics Research Initiative (OBRI) and the Real-Life Evaluation of Rheumatoid Arthritis in Canadians Receiving HUMIRA (REACH)], and to dat...

2012
Daniel F McWilliams Weiya Zhang Josephine S Mansell Patrick D W Kiely Adam Young David A Walsh

OBJECTIVE To investigate possible predictors for lack of pain improvement after 1 year of treatment for early rheumatoid arthritis (RA). METHODS The Early Rheumatoid Arthritis Network (ERAN) database was used for analysis of baseline and 1-year pain data. The ERAN is a hospital-based inception cohort of 1,189 people. Short Form 36 questionnaire bodily pain scores were used to calculate change...

Journal: :Arthritis Research & Therapy 2005
Daniel Aletaha Valerie PK Nell Tanja Stamm Martin Uffmann Stephan Pflugbeil Klaus Machold Josef S Smolen

INTRODUCTION Frequent assessments of rheumatoid arthritis (RA) disease activity allow timely adaptation of therapy, which is essential in preventing disease progression. However, values of acute phase reactants (APRs) are needed to calculate current composite activity indices, such as the Disease Activity Score (DAS)28, the DAS28-CRP (i.e. the DAS28 using C-reactive protein instead of erythrocy...

2018
Josef S. Smolen Annette Szumski Andrew S. Koenig Thomas V. Jones Lisa Marshall

BACKGROUND The aim was to analyze characteristics that predict remission induction and subsequent loss of remission in patients with moderately active rheumatoid arthritis (RA) who received full-dose combination etanercept plus methotrexate induction therapy followed by reduced-dose etanercept or etanercept withdrawal. METHODS Patients with Disease Activity Score based on 28-joint count (DAS2...

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