Zebrafish encodes several sialidases belonging to the NEU3 group, plasma membrane-associated member of family with high specificity toward ganglioside substrates. Neu3.1, Neu3.2 and Neu 3.3 have been expressed in E. coli purified using pGEX-2T expression system. Although all enzymes are by bacterial cells, Neu3.1 formed insoluble aggregates that hampered its purification. Neu3.3 oligomers as de...

Zebrafish (Danio rerio) is a teleost fish, common in home aquarium. This animal has emerged as a powerful model organism for studies of vertebrate development, diseases, biological pathways, toxicology mechanisms and organ regeneration. The adult teleost fish has the capacity to regenerate several organs, including their appendages, optic nerve, heart, spinal cord. These organs display poor reg...

T-box genes are conserved in all animal species. We have identified two members of the T-box gene family from the zebrafish, Danio rerio. Zf-tbr1 and zf-tbx3 share high amino acid identity with human, murine, chick and Xenopus orthologs and are expressed in specific regions during zebrafish development.

We have identified a novel Sox gene in zebrafish (Danio rerio), Sox31, closely related to mammalian group B Sox genes. The gene is maternally expressed. Zygotic transcription starts at gastrulation, in the presumptive neuroectoderm. Later, expression is restricted to the developing central nervous system, including forebrain, midbrain, hindbrain and spinal cord.

Differential transcriptional modulation of duplicated fatty acid-binding protein genes by dietary fatty acids in zebrafish (Danio rerio): evidence for subfunctionalization and neofunctionalization of duplicated genes BMC Evolutionary Biology 2009, 9:219 doi:10.1186/1471-2148-9-219 Santhosh Karanth ([email protected]) Santosh P Lall ([email protected]) Eileen M Denovan-Wright (emdenova@d...