Activation of cardiac sympathetic nerves is recognized as a triggering factor for cardiac arrhythmias. However, the mechanisms involved have only been speculated. Because evidence from studies in vitro has established a relation between catecholamines, delayed afterdepolarizations (DAD), and triggered rhythms, it seemed possible that in vivo adrenergic activation also might lead to the developm...

OBJECTIVE Pressure ulcer development is a quality of care indicator, as pressure ulcers are potentially preventable. Yet pressure ulcer is a leading cause of morbidity, discomfort and additional healthcare costs for inpatients. Methods are lacking for accurate surveillance of pressure ulcer in hospitals to track occurrences and evaluate care improvement strategies. The main study aim was to val...

BACKGROUND Obesity is a pervasive problem and a popular subject of academic assessment. The ability to take advantage of existing data, such as administrative databases, to study obesity is appealing. The objective of our study was to assess the validity of obesity coding in an administrative database and compare the association between obesity and outcomes in an administrative database versus ...

Anti-melanoma differentiation-associated gene 5 (MDA5) antibodies are specific indicators of patients with dermatomyositis, particularly clinically amyopathic dermatomyositis (CADM). CADM is occasionally accompanied by fatal, treatment-resistant, rapidly-progressive interstitial lung disease (RP-ILD). All previous reports showed that histopathological findings in RP-ILD with anti-MDA5 antibody-...

DDBJ/EMBL/GenBank International Nucleotide Sequence Database is still increasing, keeping doubling time only slightly longer than one year for the last these years. This situation affects the increase of DDBJ Amino acid sequence Database (DAD) [4], which is made from translation of nucleotide sequences in CDS regions annotated in DDBJ [3], and makes computation time for homology search of DAD l...

OBJECTIVES Patients with Alzheimer's disease (AD) showing a selective impairment of episodic and semantic memory have recently been classified as affected by focal temporal lobe dysfunction (FTLD) and considered as a distinct subgroup of patients affected by a particular form of AD. The aim was to compare the cerebral perfusion of patients with AD with FTLD and patients with AD with the more ty...

A network of WEB based databases has been created in the EU project “EFABIS – a European Farm Animal Biodiversity Information System” for the recording and dissemination of biodiversity data of breeds in animal agriculture. It integrates the historical database from the European Association of Animal Sciences (EAAP) and the world wide DAD-IS system of FAO in Rome. Its outstanding features are a...

This paper (a) describes a defender-attacker-defender sequential game model (DAD) to plan defenses for an infrastructure system that will enhance that system’s resilience against attacks by an intelligent adversary, (b) describes a realistic formulation of DAD for defending a transportation network, (c) develops a decomposition algorithm for solving this instance of DAD and others, and (d) demo...

Acute interstitial pneumonia (AIP) is a term used for an idiopathic form of acute lung injury characterized clinically by acute respiratory failure with bilateral lung infiltrates and histologically by diffuse alveolar damage (DAD), a combination of findings previously known as the Hamman-Rich syndrome. This review aims to clarify the diagnostic criteria of AIP, its relationship with DAD and ac...