Schisandrin B is a hepatoprotective component isolated from a traditional Chinese herb, Schisandra chinensis (Turcz.) Baill. This study determined the effect of Schisandrin B on d-galactosamine -induced liver injury and the role of heat shock proteins 27 and 70 against liver injury in mice. Acute liver injury was induced by intraperitoneal injection of d-galactosamine to mice, and Schisandrin B...

Experiments involving affinity chromatography on immobilized plasminogen columns and the concomitant use of plasmin and carboxypeptidase B indicate that the COOH-terminal lysine residues formed by plasmin-catalyzed cleavage of fibrinogen are essential for the high-affinity binding of the resulting cleavage products to plasminogen.

this study was conducted to assess the preventive effect of aqueous extract of berberis integerrima bge. root (aebir) on liver damage and oxidative stress induced by diabetes mellitus in rats. forty male rats were divided into 5 groups as follows: 1- normal (n); 2- normal + barberry (n+b) (they received barberry root extract for 6 weeks); 3- diabetic (d) (they received streptozotocin (stz), 65 ...

Six hundred 1-d-old male broilers (Ross 308) were assigned to four experimental groups; each was composed of 5 floor pen replications of 30 birds including control (no enalapril), 15, 30 and 60 ppm enalapril in the drinking water. From d 21 to 49, all the chicks were exposed to low ambient temperature to induce ascites. Mortalities were inspected to determine the cause of death and diagnose of ...

Gallic acid (3,4,5-trihydroxybenzoic acid), is a natural product found in various foods and herbs that are well known as powerful antioxidants. Our previous report demonstrated that it inhibits mast cell-derived inflammatory allergic reactions by blocking histamine release and pro-inflammatory cytokine expression. In this report, various amide analogs of gallic acid have been synthesized by int...

The single oral administration of red ginseng oil (5000 mg/kg) to Sprague-Dawley rats induced no changes in behavioral patterns, clinical signs, and body weight, and hepatotoxicity parameters such as aspartate aminotransferase and alanine aminotransferase for 14 d. Therefore, these results suggest that the red ginseng oil is safe and nontoxic acutely.

background: preterm premature rupture of membranes (pprom) occurs in 3% of pregnancies and 30-40% of preterm labors are related to this problem. early diagnosis of pprom is very important due to its impact on pregnancy outcomes. objective: to determine the diagnostic value of aspartate aminotransferase (ast) and alanine aminotransferase (alt) levels in vaginal fluid for the diagnosis of preterm...