نتایج جستجو برای: cytogenetic effects

تعداد نتایج: 1555618  

Journal: :International Journal of Environmental Research and Public Health 2005

Journal: :The Medical journal of Malaysia 2006
P C Bee G G Gan A Teh A R Haris

This study was done to assess the overall response rate of imatinib mesylate in local patients with chronic myeloid leukaemia. A total of 69 patients were recruited with male/female ratio of 7:3. Of the 69 patients; 35% were in the chronic phase, 41% were in the accelerated phase, 17% were in blast crisis and the remaining 7% were after stem cell transplantation. Complete haematological respons...

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2002
Hagop M Kantarjian Susan O'Brien Jorge E Cortes Terry L Smith Mary Beth Rios Jianqin Shan Ying Yang Francis J Giles Deborah A Thomas Stefan Faderl Guillermo Garcia-Manero Sima Jeha William Wierda Jean-Pierre J Issa Steven M Kornblau Michael Keating Debra Resta Renaud Capdeville Moshe Talpaz

PURPOSE Imatinib mesylate, a specific Bcr-Abl tyrosine kinase inhibitor, has shown encouraging activity in chronic myelogenous leukemia (CML). EXPERIMENTAL DESIGN We treated 237 patients (median age, 50 years; age range, 18-82 years) with Philadelphia chromosome (Ph)-positive accelerated-phase CML with oral imatinib mesylate at daily doses of 400 mg (26 patients) or 600 mg (211 patients) and ...

Journal: :Blood 2000
M L Slovak K J Kopecky P A Cassileth D H Harrington K S Theil A Mohamed E Paietta C L Willman D R Head J M Rowe S J Forman F R Appelbaum

The associations of cytogenetics with complete remission (CR) rates, overall survival (OS), and outcomes after CR were studied in 609 previously untreated AML patients younger than 56 years old in a clinical trial comparing 3 intensive postremission therapies: intensive chemotherapy, autologous transplantation (ABMT), or allogeneic bone marrow transplantation (alloBMT) from matched related dono...

Journal: :Journal of Environmental & Analytical Toxicology 2014

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