نتایج جستجو برای: cytochrome p

تعداد نتایج: 1306848  

Journal: :iranian journal of pharmaceutical sciences 0
hossein niknahad pharmaceutical sciences research center, and school of pharmacy, shiraz university of medical sciences, shiraz, iran. peter j. o brien faculty of pharmacy, university of toronto, toronto, ontario, canada

it has been proposed that organic nitrates such as glyceryl trinitrate (gtn), used in the treatment of cardiovascular diseases, act by producing nitric oxide (no). however, the biochemical pathway for no formation from gtn is not well understood. in the present study, we showed that nitrate formation from gtn, by isolated rat hepatocytes, was inhibited about 50% when cellular glutathione was de...

Introduction: Oxygenated water intake can increase cell death markers by increasing free radicals; however, sport activities and antioxidant substances can prevent some symptoms of free radical production. The purpose of this study was to investigate the effect of endurance training (ET) and purslane (portulaca oleracea) seed (PO) consumption on cytochrome-C and malondialdehyde...

2011
Numan Oezguen Santosh Kumar

Rational approaches have been extensively used to investigate the role of active site residues in cytochrome P450 (CYP) functions. However, recent studies using random mutagenesis suggest an important role for non-active site residues in CYP functions. Meta-analysis of the random mutants showed that 75% of the functionally important non-active site residues are present in 20% of the entire prot...

Journal: :Journal of the agricultural chemical society of Japan 1992

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