The expression of cytokeratin polypeptides in squamous metaplasia of the human uterine cervix was investigated by immunocytochemical labeling with polypeptide-specific antibodies against cytokeratins. Immunofluorescence microscopic examination of cervical tissues using various monoclonal antibodies indicated that squamous cervical metaplasia expresses a unique set of cytokeratin polypeptides, t...

ABSTRACT Squamous metaplasia of the rete ovarii is an ovarian pathologic change characterized by replacement normal single layered cuboidal epithelium a stratified squamous keratinized epithelium. Uterus and ovaries from local slaughterhouse pregnant crossbreed cow were evaluated through ultrasound, macroscopically histologically. Grossly, there multiple cysts in both ovaries, which histologica...

Basal cell adenocarcinoma is a rare salivary gland tumour, especially in minor glands. The clinical, histological, and immunohistochemical features of a case involving the palate are described. Formalin fixed, paraffin embedded sections of the tumour were examined in haematoxylin and eosin (H&E) sections and also using immunostaining for cytokeratins 7, 8, 13, 14, 18, 19, vimentin, muscle speci...

Keratinizing squamous metaplasia of the bladder is rare and is usually associated with urinary tract infections and chronic irritation. It is considered a precancerous condition of squamous cell carcinoma, especially when more than 50% of the bladder surface is affected. Medical treatment cannot eradicate this lesion. When it is limited to a small area of the bladder, transurethral resection is...

BACKGROUND Stratified keratinizing squamous epithelium in the ovary has been associated with the diagnosis of ovarian teratoma in cows. Recently, the diagnosis of "epidermoid cyst" has been proposed. A case of squamous metaplasia of the rete ovarii in a Zebu cow is described in this report. CASE PRESENTATION A crossbreed Zebu cow had both ovaries enlarged with multiple cysts. Most cysts were ...

Squamous metaplasia is an abnormal epithelial differentiation represented on the ocular surface by a spectrum of skin-like changes of conjunctival and corneal epithelium. This pathologic condition can be observed in a variety of ocular surface disorders, including systemic vitamin A deficiency and cicatricial keratoconjunctivitis. We recently encountered a patient with a progressively enlarging...

A 6-year old patient presented with an intra and suprasellar cystic lesion accompanied with impairment of the hypothalamic-pituitary axis and partial hypopituitarism. The most likely cause of sellar lesions in this age group are adamantinomatous craniopharyngioma (adaCP) or Rathke´s cleft cysts (RCCs). AdaCP are characterized by CTNNB1 mutations accompanied with aberrant nuclear beta-catenin ex...

Four cases are reported in each of which squamous epithelium was an incidental finding in surgically excised thyroid gland tissue. The occasional thyroid cyst lined throughout by squamous cells probably represents a persistent ultimo-branchial body, but the evidence indicates that the usual source of such cells in this gland is metaplasia of the follicular epithelium. An explanation is offered ...

attended our hospital for a surveillance colonoscopy. He had been diagnosed with left−sided ulcerative colitis, which had been well controlled by oral 5−ami− nosalicylic acid for 6 years. No active in− flammation was detected in the colon or rectum at colonoscopy, but a small whit− ish area with a clearly demarcated border, about 5 mm in size, was found in the low− er part of rectum (l" Fig. 1)...

Occupational exposure to wood dust is a strong risk factor for the development of intestinal-type sinonasal adenocarcinoma (ITAC); however, knowledge on possible precursor lesions or biomarkers is limited. Fifty-one samples of tumor-adjacent mucosa and 19 control samples of mucosa from the unaffected fossa of ITAC patients were evaluated for histological changes and p53 protein expression. Mild...