Cervical spondylotic myelopathy (CSM) is the most common spinal cord disorder and a major cause of disability in adults. Improvements following surgical decompression are limited and patients often remain severely disabled. Post mortem studies indicate that CSM is associated with profound axonal loss. However, our understanding of the pathophysiology of CSM remains limited.To investigate the hy...

Morphometric investigations comparing normal and affected animals increase our understanding of spinal diseases in dogs. The aim of this study was to generate morphometric data for osseous-associated cervical spondylomyelopathy (CSM) in Great Danes (GDs). Magnetic resonance imaging (MRI) morphometric features of the cervical vertebral column of GDs with and without clinical signs of CSM were ch...

OBJECTIVE To characterize and compare the MRI morphological features of the cervical vertebral column of Great Danes with and without clinical signs of cervical spondylomyelopathy (CSM). DESIGN Prospective cohort study. ANIMALS 30 Great Danes (15 clinically normal and 15 CSM-affected). PROCEDURES All dogs underwent MRI of the cervical vertebral column (C2-3 through T1-2). Features evaluat...

This project was undertaken to compare growth, meat quality, and diet digestibility when pigs were fed cafeteria food waste (FW) or a corn/soybean meal (CSM) diet. Cafeteria food waste (36 samples) fed in the growing and finishing experiment averaged 22.4% DM, 21.4% CP, 14.1% ADF, 27.2% ether extract, and 3.2% ash. The first experiment used 50 crossbred pigs randomly assigned to four diets. Dur...

BACKGROUND The direction of impulse propagation across the coronary sinus (CS) musculature (CSM) is an important piece of the mechanistic puzzle underlying atrial tachyarrhythmias. We hypothesized that in the general population, the sequence of left atrial (LA) to CSM electrograms recorded in the CS reflects the direction of impulse propagation over the CSM. METHODS We studied 19 patients wit...

AIMS This study was conducted to evaluate the clinical and MRI profiles in acute cancer strokes, and to demonstrate our experience with thrombolytic therapy in cancer stroke patients. METHODS We prospectively studied active cancer patients with acute ischemic stroke who underwent MRI within 48 h of the onset of symptoms. Patients were grouped based on the presence of conventional stroke mecha...

Aims The prevalence of positive carotid sinus massage (CSM) in asymptomatic elderly persons and related risk of syncope are poorly known. Methods and results We examined the ability of CSM to predict the risk of profound bradycardia or syncope in 30 patients with Alzheimer’s disease (AD) and no history of syncope, before treatment with cholinesterase inhibitors. Carotid sinus massage was repeat...

The present experiment was conducted to determine the digestible energy (DE), metabolizable energy (ME) content, and the apparent total tract digestibility (ATTD) of energy in growing pigs fed diets containing one of ten cottonseed meals (CSM) collected from different provinces of China and to develop in vitro prediction equations for DE and ME content from chemical composition of the CSM sampl...

A methodology for fMRI data analysis confined to the cortex, Cortical Surface Mapping (CSM), is presented. CSM retains the flexibility of the General Linear Model based estimation, but the procedures involved are adapted to operate on the cortical surface, while avoiding to resort to explicit flattening. The methodology is tested by means of simulations and application to a real fMRI protocol. ...