The aim of the present work is to analyze the cerebrospinal fluid proteomic profile, trying to find possible biomarkers of the effects of hypertension of the blood to CSF barrier disruption in the brain and their participation in the cholesterol and β-amyloid metabolism and inflammatory processes. Cerebrospinal fluid (CSF) is a system linked to the brain and its composition can be altered not o...

objective: embryonic cerebrospinal fluid (e-csf) has an important role in development of embryonic and adult brain. proteomic analysis suggests that this fluid has many morphogenes and cytokines that alter in time and space throughout embryonic life. the aim of this study was to evaluate the developmental effect of embryonic csf on proliferation and differentiation of neuroprogenitor cells in d...

Abstract Introduction Pilocytic astrocytoma of the cerebellopontine angle (CPA) is uncommon, and its spread to cerebrospinal fluid (CSF) at time diagnosis has not been reported in literature. Case Presentation We report case a 33-year-old man with multifocal pilocytic diagnosed by magnetic resonance imaging (MRI) confirmed histopathological examination, present radiological findings. Conclusion...

1. Kronholm V, Lintrup J. Spectrophotometric investigation of the cerebrospinal fluid in the near-ultraviolet region. Acta Psychiatr Neurol Scand 1960;35: 314–29. 2. Buruma OJS, Janson HLF, van den Bergh FAJTM, Bots GTAM. Blood stained cerebrospinal fluid: traumatic puncture or haemorrhage? J Neurol Neurosurg Psychiatr 1981;44:144–7. 3. Vermeulen M, Gijn van J, Bleijenberg BG. Spectrophotometri...

CEREBROSPINAL FLUID PRESSURE Evidence supports the association of low cerebrospinal fluid (CSF) pressure with the prevalence of glaucoma, particularly with respect to normal-tension glaucoma (NTG). The most robust study comes from Tongren Hospital in Beijing, China, in which patients with both high-tension and normal-tension open-angle glaucoma as well as healthy controls underwent lumbar punct...

INTRODUCTION Previous studies have shown that serum uric acid (UA) modulates outcomes of neurological diseases, although little is known about cerebrospinal fluid (CSF) UA levels in neuromyelitis optica spectrum disorders (NMOSDs). METHODS Cerebrospinal fluid and serum UA levels were measured in samples from 68 patients, including NMOSDs during relapse (n = 38) and controls with noninflammato...

References 1. Meurman OH, Irjala K, Suonpaa J, Laurent B. A new method for the identification of cerebrospinal fluid leakage. Acta Otolaryngol 1979;87: 366–9. 2. Oberascher G. Cerebrospinal otorrhea-cerebrospinal rhinorrhea. The Salzburg concept of cerebrospinal fluid diagnosis. Laryngol Rhinol Otol (Stuttg) 1988; 67:375–81. 3. Reisinger PW, Hochstrasser K. The diagnosis of CSF fistulae on the ...

We report two cases of superficial siderosis (SS) of the central nervous system (CNS), which is caused by chronic haemorrhaging into the subarachnoid space with haemosiderin deposition in the superficial portion of the CNS. Patient 1 had fluid collection in the spinal canal, which was reported as the source of the chronic bleeding. Patient 2 was bleeding from thickened dura at the level of the ...

BACKGROUND Despite recent advances in therapy that have improved the overall disease course in multiple sclerosis (MS), the prognosis at the outset remains unpredictable. OBJECTIVES To investigate whether cerebrospinal fluid (CSF) osteopontin levels correlate with disability or active disease in MS and to determine whether elevated CSF osteopontin levels are only seen in MS. DESIGN Cerebros...