Cardiac conduction system pacing, in the form of His-Cardiac Resynchronization therapy (His-CRT), is advantageous due to its physiological nature and accompanying clinical benefits.His-CRT has not become mainstream practice, challenges such as higher procedural time, pacing thresholds varying success rates. There a paucity studies comparing His-CRT with other modalities Left Bundle Branch Paced...

The CRT (creatine transporter) is a member of the Na+- and Cl--dependent neurotransmitter transporter family and is responsible for the import of creatine into cells, and thus is important for cellular energy metabolism. We established for CRT an expression system in HEK-293 cells that allowed biochemical, immunological and functional analysis of CRT wild-type and glycosylation-deficient mutant...

Cardiac resynchronisation therapy (CRT) emerged more than a decade ago as a useful form of device therapy for heart failure associated with abnormal ventricular conduction indicated by a wide QRS complex [1, 2]. According to the Guidelines of the European Society of Cardiology (ESC) entitled Cardiac Pacing and Cardiac Resynchronization Therapy (ESC Clinical Practice Guidelines, 2013), CRT has c...

BACKGROUND To evaluate the risks and benefits of endoscopic submucosal dissection (ESD) in addition to chemoradiotherapy (CRT) for the treatment of superficial esophageal squamous cell carcinoma (SESCC). METHODS AND MATERIALS We retrospectively reviewed the treatment outcomes of 47 patients with SESCC treated between October 2000 and December 2011. Sixteen patients with invasion into the subm...

OBJECTIVE Studies have shown beneficial effects of cardiac resynchronisation therapy (CRT) on mortality among patients with heart failure. However the incremental benefits in survival from CRT with a defibrillator (CRT-D) are unclear. The choice of appropriate device remains unanswered. METHOD This is a single-centre observational study in a tertiary cardiac centre. Patients (n=500) implanted...

BACKGROUND Cardiac resynchronization therapy (CRT) using biventricular pacing improves symptoms and functional capacity in patients with moderate to severe heart failure. The present study examined whether an improvement in ventricular performance from resynchronization therapy changes the autonomic control of heart rate. METHODS AND RESULTS Heart rate variability (HRV) was examined in 50 pat...

BACKGROUND In patients with left ventricular (LV) dysfunction the mitral leaflet coaptation point (CPMA) is displaced towards the LV apex. The aim of our study was to estimate the value of CPMA measurement as a simple index regarding the acute effects of cardiac resynchronization therapy (CRT), which is coming to be an established method of treatment for congestive heart failure (CHF). METHOD...

Abstract Background There is an long-standing debate whether cardiac resynchronisation therapy-defibrillation (CRT-D) preferred over CRT-pacemaker (CRT-P). No randomised controlled trials have been designed to compare these treatments. However, several observational studies performed so far providing controversial results. Methods PubMed, CENTRAL and Embase until October 2021 were screened for ...

We embed Duquesne and Le Gall’s stable tree into a binary compact continuum random (CRT) in way that solves an open problem posed by Goldschmidt Haas. This CRT can be obtained applying recursive construction method of CRTs as presented earlier work to specific distribution string beads, i.e. interval equipped with discrete measure. also express this built replacing all branch points i.i.d. copi...

CD133 has been postulated to be a colon cancer stem cell (CSCs) marker. Recent investigations suggest that CSCs might contribute to cancer recurrence and resistance to conventional therapies. This study aimed to evaluate the role of CD133 in residual cancer cells after chemoradiotherapy (CRT) for rectal cancer. Forty patients with rectal cancer underwent CRT followed by surgery. Total RNAs of r...