Abstract Background Adequate infliximab (IFX) concentrations during induction treatment are predictive for deep remission (corticosteroid-free clinical and endoscopic remission) at six months in children with Crohn’s disease (CD) ulcerative colitis (UC).1 Under standard IFX dosing, often have low trough concentrations.2 Model-informed precision dosing (MIPD) is advocated as a promising strategy...

Crohn's disease (CD) is an inflammatory disease of the gastrointestinal tract (GIT) tract and can affect several parts of the digestive system. There is a relationship between impaired mucosal barrier in the GIT of inflammatory bowel disease patients and the role of bacteria such as Mycobacterium avium paratuberculosis in CD. Apart from different therapeutic approaches for treating CD, developm...

the association of celiac disease and type i diabetes mellitus has been known for some time. this study was undertaken to investigate the prevalence of celiac disease (cd) in diabetic children and adolescents. eighty-seven patients (44 females, 43 males) aged 2- 18 years, with type i diabetes participated in this study. a group of 87 healthy unrelated girls and boys matched for age and gender s...

aim : the aim of this study was to search for metabolic biomarkers of crohn’s disease (cd). background : crohn's disease (cd) is a type of inflammatory bowel disease that causing a wide variety of symptoms. cd can influence any part of the gastrointestinal tract from mouth to anus. cd is not easily diagnosed because monitoring tools are currently insufficient. thus, the discovery of proper meth...