BACKGROUND Recent studies suggest an association between polyunsaturated fatty acids (PUFAs) and the development of chronic kidney disease. The aim of this study was to examine the relationship between PUFAs and renal function in older adults. METHODS We performed a cross-sectional and prospective analysis of 931 adults, > or = 65 years old, enrolled in the InCHIANTI study, a population-based...

conclusions vancomycin nephrotoxicity is common but usually reversible and has readily manageable adverse effect. urine kim-1 was not more accurate than serum or urine creatinine in detecting vancomycin nephrotoxicity in our study population. results thirteen out of the 52 recruited patients (25%) developed nephrotoxicity, with a mean ± standard deviation onset of 11.46 ± 7.56 days. furosemide ...

Objective: To determine the creatinine concentration in phosphate buffered saline solution and serum with different bilirubin concentrationsusing Jaffe reaction Creatinase method.Methods: In Phase 1, concentrations dilution series were 0, 2, 3, 4, 5, 6, 7, 8, 9 mg/dL 9, 12, 15,18, 21, 24, 27, 30 mg/dL, respectively. Each was spiked eleven used 1. Phase2, values 0.51, 2.41 7.33 11 concentrations...

Introduction Automated acute kidney injury (AKI) electronic alerts are based on comparing creatinine with historic results. Methods We report the significance of AKI defined by 3 "rules" differing in the time period from which the baseline creatinine is obtained, and AKI with creatinine within the normal range. Results A total of 47,090 incident episodes of AKI occurred between November 201...

Serum creatinine is commonly used as a marker of renal function, but increases in serum creatininemight not represent changes in glomerular filtration rate (GFR). INCB039110 (2-(3-(4-(7H-pyrrolo[2,3-day]pyrimidin4-yl)-1H-pyrazol-1-yl)-1-(1-(3-fluoro-2-(trifluoromethyl)isonicotinoyl) piperidin-4-yl)azetidin-3-yl)acetonitrile) is an inhibitor of the Janus kinases (JAKs) with selectivity for JAK1....

This is the second of two articles that together aim to explore current understanding of the clinical value of measuring serum/plasma urea concentration. The main focus of the first article [1] was physiological topics, such as urea production and renal processing of urea. The causes of increased and reduced plasma/serum urea concentration were also discussed. The main focus of this second arti...

In order to enlarge the scope of the calorimetric method for the determination of creatinine and creatine it is, I think, necessary to replace the bichromate standard with standard creatinine solutions, and in the next two papers will be described various adaptations of the method based on this principle. In connection with this work I have again gone over the subject of the preparation of crea...