Recommended Citation Boylston, Jennifer A.. "FHIT inactivation combined with cigarette smoke enhances the oxidative stress response. ACKNOWLEDGEMENTS Foremost, I'd like to thank the members of the Brenner Laboratory, each of whom helped to make my research both successful and enjoyable. I would like to highlight the contributions of my mentor, Charles Brenner, who helped to not only develop thi...

As soon as an abnormal globin was found to cause sickle cell disease, scientists began looking for other variations. Samples were readily available from donors or from blood samples collected for medical tests. Within a few years, many alterations were identified; some changed the alpha globin amino acid sequence and others altered the beta chain. Most of the new alleles were named for the loca...

While multiple testing procedures have been the focus of much statistical research, an important facet of the problem is how to deal with possible confounding. Procedures have been developed by authors in genetics and statistics. In this chapter, we relate these proposals. We propose two new multiple testing approaches within this framework. The first combines sensitivity analysis methods with ...

The paper discusses comparative generic sentences As are F-er than Bs—girls do better than boys in grade school, for example—which pose severe problems for extant accounts. In their stead, the paper proposes reconceiving the LF of generic sentences as more closely akin to that of sentences containing non-generic plurals, paradigmatically plural definite descriptions. Given this one crucial chan...

We study social decision schemes (SDSs), i.e., functions that map a collection of individual preferences over alternatives to a lottery over the alternatives. Depending on how preferences over alternatives are extended to preferences over lotteries, there are varying degrees of efficiency and strategyproofness. In this paper, we consider four such preference extensions: stochastic dominance (SD...