Enhanced cough response has been frequently observed in chronic cough. Recently, extrathoracic airway constriction to inhaled histamine was demonstrated in some chronic cough patients. However, relation between extrathoracic airway hyperresponsiveness (EAHR) and cough sensitivity determined by capsaicin inhalation is unclear in each etiological entity of chronic cough. Seventy-seven patients, w...

Background . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 481 Management strategy . . . . . . . . . . . . . . . . . . . . 481 The epidemiology of chronic chough . . . . . . . . . . . . 482 Chronic cough in adults . . . . . . . . . . . . . . . . . . 482 Chronic cough in childhood . . . . . . . . . . . . . . . 482 Clinical history and examination of the patient with chronic cough . . ....

Cough-related variables such as cough frequency, time to onset (i.e. the time until the first cough occurs) and the cough index (i.e. the ratio between the cough frequency and the time to onset) may be important when interpreting results of cough challenges for therapeutic interventions or for comparative research purposes. Nevertheless, repeatability (or reproducibility) for these widely used ...

Chronic cough is a common problem in childhood. Viral infections are the most prevalent cause, but other rarer disorders should be excluded whenever cough appears unusually severe and/or frequent, and when there is evidence of failure to thrive and growth retardation. The younger the child, the more the need to exclude underlying disease at an early stage. Passive smoking is an important contri...

Objective: This study aimed to systematically evaluate the prevalence of psychogenic cough in patients with chronic cough in China by meta-analysis, which may provide evidence for the empirical diagnosis and treatment of chronic cough and for the updating of related guidelines. Methods: Based on the pre-defined inclusion and exclusion criteria, studies were searched in databases. Studies (Engli...