BACKGROUND Other than the UK, The Netherlands has no formal threshold for cost-per-QALY values defined yet. For example, a cutoff value at €20,000 per QALY is sometimes mentioned in various discussions, however it has no formal status at all. Yet, since 2005, all new innovative do have to go through a cost-effectiveness evaluation though, with the assessment being focused on the methodology rat...

PURPOSE The purpose of this study was to conduct a cost effectiveness analysis of strategies designed to improve national cervical cancer screening rates, along with a distributional cost effectiveness analysis that considers regional disparities. MATERIALS AND METHODS Cost effectiveness analysis was conducted using a Markov cohort simulation model, with quality adjusted life years as the uni...

Cost-effectiveness analysis made its first appearance in the health care literature more than 4 decades ago. In Britain, the National Institute of Clinical Excellence (NICE) explicitly considers cost per quality-adjusted life year (QALY) gained among its criteria for coverage recommendations to the National Health Service; some observers have inferred that explicit criteria such as £30,000 per ...

BACKGROUND Falls among older people are of growing concern globally. Implementing cost-effective strategies for their prevention is of utmost importance given the ageing population and associated potential for increased costs of fall-related injury over the next decades. The purpose of this study was to undertake a cost-utility analysis and secondary cost-effectiveness analysis from a healthcar...

OBJECTIVES A recent randomized, controlled trial in chronic heart failure patients showed that NT-proBNP-guided, intensive patient management (BMC) on top of multidisciplinary care reduced all-cause mortality and heart failure hospitalizations compared with multidisciplinary care (MC) or usual care (UC). We now performed a cost-utility analysis of these interventions from a payer's perspective....

Health risks are commonly quantified using either of two alternative measures, willingness to pay (WTP) and quality-adjusted life years (QALYs). The relationship between these measures is of interest for comparing benefit-cost analysis (which uses WTP) with cost-effectiveness analysis (which uses QALYs), identifying a threshold for determining which health interventions are cost-effective, and ...

An article published in this Journal argued that New Zealand does not apply a cost-effectiveness threshold because medicines are funded within a fixed budget and because cost-effectiveness is only one of nine criteria that inform decisions. This Comment has explained that, from a theoretical perspective, the cost-effectiveness threshold model is not inconsistent with these two arguments. The ob...

OBJECTIVE There are few health economic evaluations of parenting programs with quality-adjusted life-years (QALYs) as the outcome measure. The objective of this study was, therefore, to conduct a cost-effectiveness analysis of the universal parenting program All Children in Focus (ABC). The goals were to estimate the costs of program implementation, investigate the health effects of the program...

OBJECTIVES In health technology assessment (HTA) agencies where cost-effectiveness plays a role in decision-making, an incremental cost-effectiveness ratio (ICER) threshold is often used to inform reimbursement decisions. The acceptance of submissions with ICERs higher than the threshold was assessed across different agencies and across indications, in order to inform future reimbursement submi...