it  is  well  known  that  desensitization  treatment  with  aspirin  can  significantly  improve symptoms and quality of life in patient with aspirin-exacerbated respiratory disease. however, its mechanism has not been clearly understood yet. in this case report, 41-year-old male patient was referred to our allergy and immunology department with complaints of chronic rhinosinusitis including p...

purpose : churg-strauss syndrome (css) is a rare form of small vessel necrotizing vasculitis. retinal artery and vein occlusion are very rare findings in these patients and they are treated by high-dose corticosteroids and cytotoxics. we describe a rare case of css under high-dose corticosteroids and cytotoxic treatment, presenting central retinal artery occlusion (crao). case report : a 45-yea...

QUESTION Some of my pregnant patients have been prescribed various potencies of topical corticosteroids. Do these carry the same fetal risks as systemic corticosteroids? ANSWER Pregnant women can be reassured that there is no apparent increased risk of adverse fetal effects when using topical corticosteroids during pregnancy, although some data do suggest fetal growth restriction with more po...

Background: Lichen planus is a common inflammatory disease that can involve the skin, nails, mucous membrane, and hair follicles. There is a long list of topical and systemic therapies for its treatment. Methotrexarte has some characteristics that make it a good choice for generalized lichen planus. Aim: The goal of this study was to assess the effect of low dose methotrexate in generalized lic...

PURPOSE To determine the effect of intravenous corticosteroids in the acute management of pediatric orbital cellulitis with subperiosteal abscess. METHODS The inpatient records of all patients treated for orbital cellulitis with subperiosteal orbital abscess between January 2001 and August 2003 were reviewed. The use of corticosteroids, length of hospital stay, need for surgical drainage, tre...

background and aims. oral pemphigus vulgaris is a chronic autoimmune mucocutaneous intraepithelial disease that primarily affects patients over the age of fifty, resulting in mucosal ulceration and is a potentially life-threatening disease. the purpose of this study was to investigate the efficacy of dapsone in combination with systemic corticosteroids to treat the oral lesions of oral pemphigu...

Corticosteroids have been used for acute-on-chronic hepatitis B liver failure (ACHBLF) patients to inhibit overactive immunological responses. Due to the severe side effects of long-term use of corticosteroids, early identification of responders is very important for clinicians. So we conducted this study to identify efficacious indicators for response to corticosteroids. A total of 74 ACHBLF p...

For some patients, herpes zoster infections not only result in acute pain but serious consequences, including postherpetic neuralgia and damage to ocular tissues. Some authors have recommended corticosteroids for the treatment of these acute symptoms and complications. The literature concerning the use of corticosteroids for herpes zoster, however, either provides conflicting results or include...