نتایج جستجو برای: controlled trial

تعداد نتایج: 589078  

2018
Keith D. Hill Plaiwan Suttanon Sang-I Lin William W.N. Tsang Asmidawati Ashari Tengku Aizan Abd Hamid Kaela Farrier Elissa Burton

BACKGROUND There is strong research evidence for falls prevention among older people in the community setting, although most is from Western countries. Differences between countries (eg sunlight exposure, diet, environment, exercise preferences) may influence the success of implementing falls prevention approaches in Asian countries that have been shown to be effective elsewhere in the world. T...

2016
Agnes Dechartres Elizabeth G. Bond Jordan Scheer Carolina Riveros Ignacio Atal Philippe Ravaud

BACKGROUND Publication bias and other reporting bias have been well documented for journal articles, but no study has evaluated the nature of results posted at ClinicalTrials.gov. We aimed to assess how many randomized controlled trials (RCTs) with results posted at ClinicalTrials.gov report statistically significant results and whether the proportion of trials with significant results differs ...

Journal: :Contemporary clinical trials 2015
Anjali Gupta Karen J Calfas Simon J Marshall Thomas N Robinson Cheryl L Rock Jeannie S Huang Melanie Epstein-Corbin Christina Servetas Michael C Donohue Gregory J Norman Fredric Raab Gina Merchant James H Fowler William G Griswold B J Fogg Kevin Patrick

Advances in information technology and near ubiquity of the Internet have spawned novel modes of communication and unprecedented insights into human behavior via the digital footprint. Health behavior randomized controlled trials (RCTs), especially technology-based, can leverage these advances to improve the overall clinical trials management process and benefit from improvements at every stage...

Journal: :Emerging Themes in Epidemiology 2008
Helen A Weiss Judith N Wasserheit Ruanne V Barnabas Richard J Hayes Laith J Abu-Raddad

BACKGROUND Only four out of 31 completed randomized controlled trials (RCTs) of HIV prevention strategies against sexual transmission have shown significant efficacy. Poor adherence may have contributed to the lack of effect in some of these trials. In this paper we explore the impact of various levels of adherence on measured efficacy within an RCT. ANALYSIS We used simple quantitative metho...

Journal: :BMC Family Practice 2009
Ritu Jones Robert O Jones Colin McCowan Alan A Montgomery Tom Fahey

BACKGROUND A criticism of Randomized Controlled Trials (RCTs) in primary care is that they lack external validity, participants being unrepresentative of the wider population. Our aim was to determine whether published primary care-based RCTs report information about how the study sample is assembled, and whether this is associated with RCT characteristics. METHODS We reviewed RCTs published ...

Background: Among manuscripts submitted to biomedical journals, randomized controlled trials (RCTs) form the backbone of evidence-based medicine. Hence, their protocol should be designed rigorously and their results should be reported clearly. To improve the quality of RCT reporting, researchers developed the CONSORT Statement in 1996 and updated it in 2010. This study was designed to assess th...

2008
Allan Abbass

This study evaluated the efficacy and long-term effectiveness of intensive short-term dynamic psychotherapy (ISTDP) in the treatment of patients with DSM-IV personality disorders (PD). Twenty-seven patients with PD were randomized to treatment with ISTDP or a minimal-contact, delayed-treatment control condition. ISTDP-treated patients improved significantly more than controls on all primary out...

2006
H J Lin F Y Lee W M Kang Y T Tsai S D Lee C H Lee

We conducted a prospective randomised controlled trial of 137 patients with massive peptic ulcer haemorrhage over a period of 12 months to compare the haemostatic effects of endoscopic heat probe thermocoagulation and pure alcohol injection. Seventy eight patients (56 9%) were in shock at the time ofrandomisation to the trial. The age, sex, number of patients in shock, haemoglobin value at the ...

2003
D. G. McDEVITT

McDevitt, D. G. (1970). Brit. J. industr. Med., 27, 67-71. Ampicillin in the treatment of brucellosis: A controlled therapeutic trial. A controlled therapeutic trial has been carried out with ampicillin in the treatment of brucellosis. Sixty-eight people, veterinary surgeons or their unqualified assistants, with serological evidence of brucella antibodies measured by the antihuman globulin (Coo...

2005
Gregory K. Brown Thomas Ten Have Gregg R. Henriques

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