The ocular albinism type I (OA1) is clinically characterized by impaired visual acuity, nystagmus, iris hypopigmentation with translucency, albinotic fundus, and macular hypoplasia together with normally pigmented skin and hair. However, it is easily misdiagnosed as congenital idiopathic nystagmus in some Chinese patients with OA1 caused by the G-protein coupled receptor 143 (GPR143) gene mutat...

PURPOSE Periodic alternating nystagmus (PAN) is a spontaneous horizontal nystagmus observed in disorders of the central nervous system. Patients with congenital PAN complain of oscillating vision at high rates. Medication is the first-choice treatment for PAN; however, clinicians still seek better therapy. The aim of this study was to evaluate outcomes of recession of four horizontal rectus mus...

Congenital nystagmus is a disorder of eye movement with an associated reduction in visual acuity. The latter is mainly due to the intensity of the nystagmus (amplitude times frequency) allowing the object of regard to spend only a short time on the fovea. Training patients by an auditory feedback technique to control the nystagmus enables visual sensitivity to improve. This method is compared w...

Using a computer-generated acuity task, the resolution of vertical and horizontal Landolt Cs was assessed at three levels of contrast, each for three different crowding conditions. Eighteen adults participated; six had congenital idiopathic nystagmus, six were oculocutaneous albinos and six served as controls. Contour interaction was evident when bars were placed 1 gap-width from the Landolt C ...

SUMMARY We used ocular motility recordings to identify the characteristics of a rare combination of conjugate, horizontal jerk, and pendular nystagmus in a 9-year-old boy. The clinical diagnoses were amblyopia, left esotropia, congenital nystagmus, and an apparently uniocular pendular nystagmus that mimicked spasmus nutans. Ocular motility recordings revealed an unusual latent/manifest latent n...