OBJECTIVE To describe the clinical characteristics of intrauterine infection with lymphocytic choriomeningitis (LCM) virus, an uncommonly recognized cause of congenital viral infection. PATIENTS Three infants born in the midwestern United States in 1994 and 1995 with clinical features and serologic studies consistent with congenital LCM virus infection and cases of congenital infection identi...

BACKGROUND  Congenital cytomegalovirus (CMV) infection is the major infectious cause of birth defects and hearing loss globally. There is a growing recognition of the potential clinical impact of congenital CMV infections in high-seroprevalence settings. METHODS  A cross-sectional study of neonatal admissions at a large referral center in sub-Saharan Africa to determine the prevalence of both...

An azygos lobe is a rare anatomic variant of the lung which may be misdiagnosed as other pathological conditions. There dearth information on clinical characteristics children with lobe. This study aims to summarize features lobe, helpful improve recognition and care those patients. Clinical findings imaging were collected analyzed. In this study, 50 included. A total 28% cases found have incid...

OBJECTIVE We examined the frequency and characteristics of chromosomally integrated human herpesvirus 6 among congenitally infected children. METHODS Infants with and without congenital human herpesvirus 6 infection were prospectively monitored. Cord blood mononuclear cell, peripheral blood mononuclear cell, saliva, urine, and hair follicle samples were examined for human herpesvirus 6 DNA. H...

Received 15 May 2007; accepted 15 May 2007; electronically published 1 October 2007. Potential conflicts of interest: P.E.P. receives royalties for sales of a reagent that can be used to diagnose HHV-6 infections. J.G. declares no potential conflicts. Financial support: Cleveland Clinic. Reprints or correspondence: Dr. Philip E. Pellett, Cleveland Clinic, 9500 Euclid Ave., NN10, Cleveland, OH 4...

hyperpigmentation over face in a neonate is rare and the differentials for the same are also rare. congenital chickengunya, fungal and viral infections, drug rash are few differentials. chikungunya virus (chikv) infection manifesting in neonates is very rare. the prevalence of the entity was described only recently. we describe a neonate with hyperpigmentation on day 3 of life with stormy cours...

BACKGROUND Human cytomegalovirus (CMV) represents one of the leading causes of congenital infections worldwide. Early diagnosis of fetal infection and consequent rapid therapeutic intervention with immunoglobulin treatment may prevent fetal transmission and virus-related sequelae. In this study, the cell-mediated immunity and immunoglobulin avidity were evaluated as potential predictors of cong...