CONTEXT Congenital hearing loss affects between 1 and 3 out of every 1,000 children. Screening of all neonates has been made possible by the development of portable automated devices. Universal screening is a 2-stage screening process using automated transient-evoked otoacoustic emissions, followed when indicated by automated auditory brain response testing. Targeted screening reserves the 2-st...

OBJECTIVE To evaluate risk indicators for congenital and delayed onset hearing loss in a cohort of newborns who underwent newborn hearing screening, and to evaluate the impact of use of the Joint Committee on Infant Hearing (JCIH) recommendations on requirements for ongoing monitoring of infants identified as at risk for hearing loss. PATIENTS AND METHODS Cohort of 26,341 newborns entered in ...

(See the articles by Ogawa et al., on pages 782–8, and by Schleiss et al., on pages 789–98.) It has been 50 years since Smith [1] and Weller et al. [2] separately reported the isolation and propagation of a cytopath-ogenic virus from tissues of infants with cytomegalic inclusion disease. In the intervening half century, much has been learned about congenital cytomegalovirus (CMV) infection, as ...

Congenital human cytomegalovirus (HCMV) occurs in 0.5-1% of live births and approximately 10% of infected infants develop hearing loss. The mechanism(s) of hearing loss remain unknown. We developed a murine model of CMV induced hearing loss in which murine cytomegalovirus (MCMV) infection of newborn mice leads to hematogenous spread of virus to the inner ear, induction of inflammatory responses...

Introduction: Literature regarding the different degrees of hearing loss in patients with Cornelia de Lange syndrome (CDLS) reports that half of the affected patients exhibit severe to profound sensorineural hearing loss. We present the first pre-school child with CDLS who underwent cochlear implantation for congenital profound sensorineural hearing loss.   Case Report: A 3-year-old boy with CD...

introduction: hearing is essential for humans to communicate with one another. early diagnosis of hearing loss and intervention in neonates and infants can reduce developmental problems. the aim of the present study was to assess the prevalence of hearing impairment in newborns admitted to a neonatal intensive care unit (nicu) and analyze the associated risk factors.   materials and methods: th...