Classical eye-blink conditioning in mutant mice can be used to study the molecular mechanisms underlying associative learning. To measure the kinetic and frequency domain properties of conditioned (tone - periorbital shock procedure) and unconditioned eyelid responses in freely moving mice, we developed a method that allows adequate, absolute, and continuous determination of their eyelid moveme...

Objective: It has been shown that berberine, a major component of Berberis vulgaris extract, modulates the activity of several neurotransmitter systems including dopamine (Da) and N-methyl-D-aspartate (NMDA) contributing to rewarding and reinforcing effects of morphine. Drug craving and relapsing even after a long time of abstinence therapy are the most important problems of addiction. In the p...

This research studied the role of surface and cumulative word frequency in the processing and representation of morphologically complex suffixed words. Experiment 1 showed that auditory lexical decision times to suffixed words were influenced by their surface frequency. Experiments 2 and 3 showed a cumulative root frequency effect for highand low-surface-frequency suffixed words. Experiment 4 d...

On the example of the recent edition of the Frequency Dictionary of Czech we describe and explain some new general principles that should be followed for getting better results for practical uses of frequency dictionaries. It is mainly adopting average reduced frequency instead of absolute frequency for ordering items. The formula for calculation of the average reduced frequency is presented in...

We establish the following characteristics of the task of perspective classification: (a) using term frequencies in a document does not improve classification achieved with absence/presence features; (b) for datasets allowing the relevant comparisons, a small number of top features is found to be as effective as the full feature set and indispensable for the best achieved performance, testifyin...

Vocabulary is fundamental to reading. As elementary students cross over from learning to read into reading to learn, vocabulary knowledge becomes increasingly important. The massive amount of vocabulary a student must learn precludes large amounts of time spent on any single word (Carver 1994, Schwanenflugel et al. 1997), except perhaps for some words that the student will read and write many t...

In this study we investigate vowel reduction and the role of some lexical factors in the production of vowels extracted from a corpus of French conversations. Vowel durations and spectral quality are examined with respect to 1. their interaction in the corpus, 2. the position of vowels in words, and 3. word frequency and word category. The analyses are conducted on vowels produced by 16 speaker...

A frequently replicated finding is that higher frequency words tend to be shorter and contain more strongly reduced vowels. However, little is known about potential differences in the articulatory gestures for high vs. low frequency words. The present study made use of electromagnetic articulography to investigate the production of two German vowels, [i] and [a], embedded in high and low freque...

Unilateral cerebellar lesions abolished the occurrence of ipsilateral conditioned nictitating membrane responses during the 285 msec interval between onset of the conditioned and unconditioned stimuli on paired trials. This effect was obtained in 15 animals sustaining damage to the dorsolateral aspects of the interpositus nucleus and the adjoining white matter. However, conditioned responses di...