After modification with monomethoxyl-poly(ethylene glycol)-5000, a recombinant intracellular uricase from Bacillus fastidiosus ATCC 29604 showed residual activity of about 65%, a thermo-inactivation half-life >85 h, a circulating half-life about 20 h in rats in vivo, consistent effects of common cations, and consistent optima for reaction temperature and pH. Thus, this uricase can be formulated...

Crystals of human oxyhaemoglobin were obtained from poly(ethylene glycol) solutions. Spectroscopic and spectrophotometric measurements on the solutions during crystallization and on the dissolved crystals indicate that the method yields stable crystals of oxyhaemoglobin. Preliminary X-ray studies showed that the crystals obtained are isomorphous with those of deoxyhaemoglobin obtained from poly...

This study investigated the encapsulation of newt iris pigment epithelial cells (PECs), which have the ability to regenerate a lens by trans-differentiation in vivo, within a biodegradable hydrogel of oligo(poly(ethylene glycol) fumarate) crosslinked with poly(ethylene glycol)-diacrylate. Hydrogel beads of initial diameter of 1 mm were fabricated by a molding technique. The swelling ratio and d...

PEGylated organosilica nanoparticles have been synthesized through selfcondensation of 3-mercaptopropyltrimethoxysilane in dimethylsulfoxide into thiolated nanoparticles with their subsequent reaction with methoxypolyethylene glycol maleimide. The PEGylated nanoparticles showed excellent colloidal stability over a wide range of pHs in contrast to the parent thiolated nanoparticles, which have a...

Polyaniline (PANI) nanocomposite has been successfully prepared in aqueousmedia by the chemical polymerization of aniline with ammonium peroxydisulphateas an initiator in the presence of a steric stabilizer such as sodium dodecylbenzenesulfonate(DBSNa), Poly(vinyl pyrrolidone) (PVP), poly(vinyl alcohol)(PVA), poly(ethylene glycol) (PEG) and hydroxypropylcellulose (HPC). Thechemical structure, m...

Interpolymer complexation is associated with the formation of hydrogen bonds between pendent and/or grafted groups of a single polymer or copolymers. The degree of complexation can be described theoretically in terms of complexation/decomplexation equilibrium characteristics. Graft copolymer networks of poly(methacrylic acid-g-ethylene glycol) were prepared by free radical solution polymerizati...

Herein we report the design of a photocurable amphiphilic co-network consisting of perfluoropolyether and poly(ethylene glycol) segments that display outstanding nonfouling characteristics with respect to spores of green fouling alga Ulva when cured under high humidity conditions. The analysis of contact angle hysteresis revealed that the poly(ethylene glycol) density at the surface was enhance...

in this work, new biodegradable abcba type pentablock copolymers with different mole ratio of l-lactide and ppdo-b-peg-b-ppdo triblock copolymer were synthesized and characterized. in the first step, ppdo-b-peg-b-ppdo triblock copolymer was synthesized via a ring-opening polymerization of p-dioxanone (pdo) monomer with poly (ethylene glycol) (peg) using stannous octoate (sn(oct)2) as the cataly...

The photoelectrochemical response of nanoporous films, obtained by anodization of Ti and W substrates in a variety of corrosive media and at preselected voltages in the range from 10 to 60 V, was studied. The as-deposited films were subjected to thermal anneal and characterized by scanning electron microscopy and X-ray diffraction. Along with the anodization media developed by previous authors,...