BACKGROUND Platelet transfusion is accompanied by febrile nonhemolytic transfusion reactions. The generation of cytokines (like IL-1 beta, IL-6, IL-8, and TNF-alpha) in platelet concentrates by white cells is suggested to be responsible for febrile nonhemolytic transfusion reactions. The number of white cells in the platelet concentrates is crucial to cytokine generation. METHODS This study w...

1.5 Range of Application, Dosage, Mode of Administration 1.5.1 Indications 1.5.1.1 General Principles 1.5.1.2 Acute Blood Loss 1.5.1.3 Chronic Anemias 1.5.2 Indications for Special RBC Concentrates 1.5.2.1 Irradiated Leukocyte-Depleted RBC Concentrates 1.5.2.2 Washed RBC Concentrates 1.5.2.3 Cryopreserved RBC Concentrates 1.5.2.4 CMV and Parvovirus B19 1.5.3 Selection and Dosage of RBC Concentr...

1.5 Range of Application, Dosage, Mode of Administration 1.5.1 Indications 1.5.1.1 General Principles 1.5.1.2 Acute Blood Loss 1.5.1.3 Chronic Anemias 1.5.2 Indications for Special RBC Concentrates 1.5.2.1 Irradiated Leukocyte-Depleted RBC Concentrates 1.5.2.2 Washed RBC Concentrates 1.5.2.3 Cryopreserved RBC Concentrates 1.5.2.4 CMV and Parvovirus B19 1.5.3 Selection and Dosage of RBC Concentr...