The current study reports the results of an open label pilot study evaluating a novel treatment protocol for patients with locally advanced head and neck cancer. Patients received induction chemotherapy and those who had a clinical complete response to induction chemotherapy were offered trans-oral nidusectomy for the primary lesion and neck node dissection. If a pathologic complete response wa...

OBJECTIVE To clarify the influence of an experimental palatal plate on the mandibular position during continuous [n] phonation and at the physiological rest position in complete denture wearers. METHODS Ten complete denture wears volunteers were investigated. Two kinds of experimental palatal plate with a thickness of 3 mm and 5 mm (from the denture basal surface to denture polished surface) ...

many studies have shown the clinical importance of cd7 expression in aml patients. to evaluate the clinical importance and response to chemotherapy in cd7 positive aml, this study was conducted. from the patients, 76 cases were studied during 3 years. in 3 years of this study 70.5 percent of cd7 positive and 89.6 percent of cd7 negative patients achieved complete remission with no significant d...

Twenty patients with bulky (>4 cm size) FIGO stage IB cervical cancer were treated with cisplatin 50 mg/m2 and vincristine 1 mg/m2, administered intravenously at 10-day intervals for a total of 3 courses before radical hysterectomy. A complete clinical response was noted in 1 patient (5%) and partial response in 5 (25%). Fourteen patients (70%) had stable disease. There was no grade 3 toxic...

Objective The mortality of patients with locally advanced triple-negative breast cancer (TNBC) is high, and pathological complete response (pCR) to neoadjuvant chemotherapy (NAC) is associated with improved prognosis. This retrospective study was designed and powered to investigate the ability of 18F-fluorodeoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) to predict pat...

background familial mediterranean fever (fmf) is an autosomal recessive disorder characterized by sporadic, paroxysmal attacks of fever and serosal inflammation. although the disease usually begins before the age of 20 years, we aimed to evaluate the demogra­phy, clinical features and treatment outcome of familial mediter­ranean fever in iranian adult patients above 20 years old. methods in thi...