Sclera from donor globes was eluted in phosphate-buffered saline at 4 degrees C for 24 hr. Hemolytic assays were used to measure functional C1, C4, C2, C3, C5 and C6 in scleral eluates. Radial immunodiffusion was used to measure Factor B, a component of the alternative complement pathway, and albumin in scleral eluates. Molecular weight appeared to be a factor in determining the hemolytic activ...

Complement, an important component of the innate immune system, is comprised of about 35 individual proteins. In mammals, activation of complement results in the generation of activated protein fragments that play a role in microbial killing, phagocytosis, inflammatory reactions, immune complex clearance, and antibody production. Fish appear to possess activation pathways similar to those in ma...

The complement system, unlike the coagulation system, was largely characterized by in-vitro techniques which did not make use of genetically deficient plasmas. The existence of the genetically deficient plasmas. The existence of the genetically deficient subjects therefore has served largely to increase our knowledge of the in-vivo role of complement. At the present time its clearest role is in...

The complement system is a group of about 35 soluble and cell-surface proteins which interact to recognize, opsonize and clear or kill invading micro-organisms or altered host cells (e.g. apoptotic or necrotic cells). Complement is a major part of the innate immune system. Recognition proteins such as C1q, MBL (mannan-binding lectin) and ficolins bind to targets via charge or sugar arrays. Bind...

In the best articles, generally those dealing with basic Chromosome Puffs research, the combination of depth and accessibility is impressive. One on Hox genes introduces the notion of The Science Times Book of Genetics a conserved body plan among species, illustrating the Edited by Nicholas Wade point with the fauna of Star Trek, and continues with New York: The Lyons Press (1999). 256 pp. an e...

mumps is an acute contagious viral disease that usually manifests as inflam¬mation of the parotid glands. the disease may be associated with symptoms such as parotitis, orchitis and meningoencephalitis. 85% of cases occur in children under 15 years of age. the disease is rare below two years but increases with age, reaching a maximum at 5 to 9 years. some studies in iran showed that the highest...