Regulation of Set1-COMPASS-mediated H3K4 methylation and Dot1-mediated H3K79 methylation by H2BK123 ubiquitination (H2Bub1) is an evolutionarily conserved trans-histone crosstalk mechanism. How H2Bub1 impacts chromatin structure and affects Set1-COMPASS/Dot1 functions has not been fully defined. Ubiquitin was proposed to bind proteins to physically bridge H2Bub1 with Set1-COMPASS/Dot1. Alternat...

the geomagnetic field for two forms of spatial orientation: (1) shoreward orientation, which utilizes only directional (‘compass’) information (Phillips, 1986a,b; Phillips and Borland, 1992a,b; Deutschlander et al., 1999a,b, 2000; Phillips et al., 2001) and (2) map-based homing orientation (‘true navigation’), which utilizes both compass and geographic position (‘map’) information (Phillips, 19...

We study the single transverse-spin asymmetry for open charm production in the semiinclusive lepton-hadron deep inelastic scattering (SIDIS) and pp collision. Within collinear factorization approach, we find that the asymmetry is sensitive to the twist-3 trigluon correlation functions in the proton. With a simple model for the trigluon correlation functions, we estimate the asymmetry in SIDIS f...

Traditional expository texts typically follow formats that have been well established and predictable. However, design of hypertext systems depend to a large extent on the epistemological, instructional and design perspectives that the design team espouses. Therefore, one of the important differences in learning from hypertext compared to learning from traditional text is that students need to ...

The measurement of transverse spin effects in semi-inclusive deepinelastic scattering (SIDIS) is an important part of the COMPASS physics program. In the years 2002-2004 data was taken by scattering a 160GeV/c muon beam off a transversely polarized deuteron target. In 2007, additional data was collected on a transversely polarized proton target. New preliminary results for the Collins and Siver...

The COMPASS experiment has obtained first physics results in the field of polarized distribution functions for quarks and gluons using muon scattering off polarized deuterons. The analysis using open charm production and pairs of high pT hadrons is presented. We also have used a transversely polarized target to address transverse information for quarks inside the nucleon. In addition, a pilot r...

In this study, we evaluated the performance of a three-dimensional (3D) dose verification system, COMPASS version 3, which has a dedicated beam models and dose calculation engine. It was possible to reconstruct the 3D dose distributions in patient anatomy based on the measured fluence using the MatriXX 2D array. The COMPASS system was compared with Monte Carlo simulation (MC), glass rod dosimet...

The Set1-containing complex, COMPASS, methylates histone H3 on lysine 4 (K4) in Saccharomyces cerevisiae. Despite the preferential association of K4-trimethylated H3 with regions of the genome that are transcribed by RNA polymerase II, transcriptional silencing is one of the few cases in S. cerevisiae where histone-methylation defects have a clear effect on gene expression. To better understand...

Several studies have suggested that the magnetic compass of birds is located only in the right eye. However, here we show that night-migrating garden warblers (Sylvia borin) are able to perform magnetic compass orientation with both eyes open, with only the left eye open and with only the right eye open. We did not observe any clear lateralization of magnetic compass orientation behaviour in th...

COMPASS is a profile-based method for the detection of remote sequence similarity and the prediction of protein structure. Here we describe a recently improved public web server of COMPASS, http://prodata.swmed.edu/compass. The server features three major developments: (i) improved statistical accuracy; (ii) increased speed from parallel implementation; and (iii) new functional features facilit...