Bacterial meningitis is a life-threatening infectious disease with high mortality and disability rates, despite availability of antibiotics and adjunctive therapy with dexamethasone. Several risk factors and predisposing conditions have been identified that increase susceptibility for bacterial meningitis. Such risk factors can consist of medical conditions resulting in immunodeficiency, host g...

objectives: this paper reviews the current literature on acquired brain injury (abi) with a focus on abi burden, importance of community integration, and community integration definitions suggested by the literature. methods: literature review results: acquired brain injury (abi) is referred to a diverse range of disabilities resulted of injury in different parts of the brain. people with abi a...

This investigation aimed both to delineate the current status of community-acquired acute bacterial meningitis and to produce data on the interrelationships between clinical, laboratory and therapeutic parameters in the elderly. This retrospective cohort study was conducted in 28 Turkish institutions in 159 culture-positive patients over the age of 50 years. Streptococcus pneumoniae was the mos...

The increasing antimicrobial resistance among pathogens frequently isolated from patients with bacterial meningitis formed the rationale to perform a surveillance study to determine the prevalence of resistance in The Netherlands. Haemophilus influenzae strains (n = 316) isolated from cerebrospinal fluid (CSF), 1125 meningococcal strains isolated from blood or CSF and 398 pneumococcal strains i...

BACKGROUND Hyponatraemia in adults with bacterial meningitis has been described as a common complication, but its true prevalence and clinical importance are unknown. AIM To investigate the prevalence, clinical characteristics and consequences of hyponatraemia in bacterial meningitis in adults. DESIGN Nationwide observational cohort study. METHODS We prospectively assessed the prevalence ...