Protein design allows sequence-to-structure relationships in proteins to be examined and, potentially, new protein structures and functions to be made to order. To succeed, however, the protein-design process requires reliable rules that link protein sequence to structure?function. Although our present understanding of coiled-coil folding and assembly is not complete, through numerous bioinform...

the aim of this study was to evaluate the long-term outcome of treatment using kirschner wires and tensioning bands for tarsocrural luxation with malleolus fractures resulting from trauma in dogs. eight dogs with tarsocrural luxation due to malleolus fracture were selected. following intrathecal anesthesia, the malleolus bone was returned to its normal position using two kirschner wires and ten...

The static strain aging is a phenomenon that can change the mechanical properties of low carbon steels. Thus, the static strain aging behavior of low carbon steel wires after drawing process is studied. To do so, the wires are austenitized at different temperatures and cooled in different rates. Then the wires are drawn and aged at a specific temperature and time. Before and after aging of each...

objective: orthodontic wires should have high resistance against corrosion in the oral environment. since the effect of ph on corrosion has been well recognized, this study sought to assess and compare the electrochemical corrosion of orthodontic brackets and wires of different brands in acidic artificial saliva.   methods: this in vitro experimental study was conducted on 24 mandibular central...

Coiled coils are extensively and successfully used nowadays to rationally design multistranded structures for applications, including basic research, biotechnology, nanotechnology, materials science, and medicine. The wide range of applications as well as the important functions these structures play in almost all biological processes highlight the need for a detailed understanding of the facto...

UNLABELLED We introduce the CC+ DATABASE, a detailed, searchable repository of coiled-coil assignments, which is freely available at http://coiledcoils.chm.bris.ac.uk/ccplus. Coiled coils were identified using the program SOCKET, which locates coiled coils based on knobs-into-holes packing of side chains between alpha-helices. A method for determining the overall sequence identity of coiled-coi...

The spindle pole body (SPB) is a large multi-protein complex that organizes microtubules in yeast. Through its function of nucleating and anchoring microtubules, the SPB is essential for cell viability. High-resolution structures of the SPB have not been achieved using x-ray crystallography, due to its low copy number, large size, heterogeneous composition, and association with the nuclear memb...

Purpose: According to frequent needs to gastric decompression by nasogastric tube insertion during laparoscopic Cholecystectomy, the current comparative study was accomplished through single blind clinical trial considering both the presence and the absence of guide wire insertion. Materials and Methods: Twenty patients were selected for elective surgery of laparoscopic Cholecystectomywith ...